On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Cancer progression is an evolutionary process involving the sequential occurrence of key genetic alterations known as drivers. In prostate cancer, progression to metastasis requires multiple driver alterations, although the type and order of these invariably differs between patients. In this talk we describe how the union of multiple genomic analyses reveals that divergent evolution, mediated by drivers that induce dysregulation of androgen receptor DNA binding, results in two distinct subtypes. Our findings unify many previous molecular groupings in prostate cancer and provide a powerful new paradigm for cancer stratification.
