OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Oncogenes are not able to initiate tumours in all cellular contexts, a phenomenon referred to as oncogenic competence. Such competence depends on both cell-intrinsic programs (i.e. developmental and epigenetic state) as well as cell-extrinsic influences from the TME. To study this, we have developed zebrafish and human pluripotent stem cell models of melanoma. In the talk, I will discuss how convergence of intrinsic and extrinsic programs determines the likelihood of oncogenic transformation.