On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Tissues such as the gut and liver are enriched for “unconventional” or innate-like T cells. These cells manage to balance the competing demands of responding to microbes when they are dangerous/invasive, but otherwise maintaining a healthy homeostasis with commensals, using a combination of signals from their TCR and from cytokines. MAIT cells are one example of such cells. In this talk, I’ll discuss a new version of unconventional or innate-like behaviour shown by CD4+ T cells found in the human gut and their parallels in mice. These commensal-reactive, innate-like cells are restricted by MHC Class II and are currently termed “Tmic” cells. I’ll introduce this work which was a collaboration between the Kennedy and the TGU and discuss the implications in health and disease.
