OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Sydney Brenner’s 2002 Nobel prize lecture envisaged humans as the model organism of choice in an age of genomics. This seminar will outline our work on extreme growth disorders, a group of human single gene disorders which we have exploited to gain insights into fundamental cellular processes. I will speak about an enigmatic protein involved in DNA replication and how AI has shed light on its molecular function. I will also talk about our ongoing work on a gain of function DNMT3A mutation, where we have been using haematopoiesis to investigate how it impacts globally on cell number and organism size.
