OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Animals adapt their behaviour in response to variable changes in reward reinforcement. The prefrontal areas of the mammalian neocortex, especially the orbitofrontal cortex (OFC), play an important role in invoking rule-based strategies to enable flexible learning. However, the neural circuit mechanisms in OFC and its hierarchical interactions with sensory areas underlying such processes remain elusive. In my talk, using a tactile reversal-learning task in mice, I will discuss cellular and circuit interactions between orbitofrontal and somatosensory cortices that guide flexible tactile decision-making. I will also present data on how flexible behaviour and feedback regulation of sensory processing is disrupted in animal models of autism spectrum disorders.
