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My group are primarily interested how insulin regulates the transport of glucose into fat and muscle tissues. This process is important for lowering blood glucose after a meal, and impaired insulin-stimulated glucose uptake (or insulin resistance) is a risk factor for a number of metabolic disease including type 2 diabetes. I will discuss how we have used genomics, proteomics and phosphoproteomics analyses to shed light on new regulators of insulin-stimulated glucose transport and how this process is dysregulated in insulin resistance.