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AI hold tremendous promise for healthcare. Technologists frequently talk about ‘disrupting’ healthcare in the same way that technology has disrupted retail, communication, entertainment, and many other spheres of life. We are now seeing a culture clash, between the ‘move fast’ world of technology, and the ‘safety first’ world of medicine. What is the role of regulation in striking the right balance? How do we ensure that digital health products are safe, yet still dynamic and responsive to individual users’ needs? What’s on the horizon? What should we, as patients, clinicians, and researchers, expect?