OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
We discovered that during the early immune contraction phase of an acute infection with lymphocytic choriomeningitis virus, 2D TCR–pMHC affinity of TCR transgenic P14 T cells increased more for cells from the splenic red pulp (RP) than the white pulp (WP). This difference was governed by regulatory T cells and TGF-β. The increased 2D affinity of RP cells correlated with their increased ability to kill target cells and to recognize a CTL escape epitope. Memory precursors from WP preferentially developed into long-term memory cells as compared to cells from RP, despite expression of the same memory markers.
