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We are delighted to welcome Professor Charlotte Deane, Professor of Structural Bioinformatics at the University of Oxford, to talk on ‘AI for antibody design – going beyond the static’.
The seminar will be chaired by Dr Matthew Raybould and will take place on 30 October, from 16:00 to 17:00, in the lecture theatre of the Richard Doll Building.
Abstract
The ability of proteins to adapt their shape can be fundamental to their function. Whilst we can now computationally predict a single, static protein structure with high accuracy, we are not yet able to reliably predict structural flexibility. A major factor limiting such predictions is the scarcity of suitable training data. Professor Deane will present novel tools and databases that help to overcome this.
Biography
Charlotte Deane MBE is a Professor in the Department of Statistics at the University of Oxford, Executive Chair of the Engineering and Physical Sciences Research Council (EPSRC) and Co-Founder of Dalton Tx. During the COVID-19 pandemic, she served on SAGE, the UK Government’s Scientific Advisory Group for Emergencies, and acted as UK Research and Innovation’s COVID-19 Response Director.