The antibody repertoire generated by an animal in response to immunization results from its recognition of the target antigen, its native genetic diversification and cellular selection mechanisms, and the sequences of its immunoglobulin genes. All of these parameters are profoundly influenced by the host animal species and its genetics. OmniAb® accesses the biodiversity of four species to generate high-quality custom repertoires of human antibodies to empower therapeutic antibody discovery for a wide variety of targets and workflows.