OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The compilation of memories, collected and aggregated across a lifetime defines our human experience. My lab is interested in dissecting how memories are stored, updated, integrated and retrieved across a lifetime. Recent studies suggest that a shared neural ensemble may link distinct memories encoded close in time. Using in vivo calcium imaging (with open-source Miniscopes in freely behaving mice), TetTag transgenic system, chemogenetics, electrophysiology and novel behavioral designs, we tested how hippocampal networks temporally link memories. Multiple convergent findings suggest that contextual memories encoded close in time are linked by directing storage into overlapping hippocampal ensembles, such that the recall of one memory can trigger the recall of another temporally-related memory. Alteration of this process (e.g. during aging, PTSD, etc) affect the temporal structure of memories, thus impairing efficient recall of related information.