Spatial colocalisation of neoantigen-expressing tumour cells and cognate T-cells in cancer

Amit is a Wellcome Trust Early Career Fellow and Haematologist based at the Oxford Centre for Immuno-oncology and the Wellcome Sanger Institute’s Division of Generative Genomics. He holds a medical degree with Distinction from the University of Manchester and completed his Haematology training in South West London (Royal Marsden).
Amit completed his PhD with Professor Richard Houlston at the Institute of Cancer Research, London, investigating genetic risk factors and clinical translation for cancers. As an NIHR Academic Clinical Fellow, he worked on the 100,000 Genomes Project to define genomic and neo-antigen landscapes and actionable drug targets. Recently, he worked at the Dana-Farber Cancer Institute, Boston, in the lab of Professor Catherine Wu, advancing spatial genomic technology to genotype TCR and mutations at single-nucleus resolution. Currently, he is at the Wellcome Sanger Institute utilising mutagenesis screens in cancer.