OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
The nervous system consists of numerous specialized cell types that remain to fully cataloged and
characterized at the molecular level. Due to the high degree of structural and functional
heterogeneity and the intricate spatial organization of these cells, it is of special importance to
analyze gene expression in the presence of full morphological and spatial contexts. Due to the lack
of specific antibody reagents, especially for lncRNAs, G-protein coupled receptors (GPCRs), and ion
channels, mapping of specific transcripts by in situ hybridization offers an excellent alternative
approach. The RNAscope® assay provides a powerful method to detect gene expression within the
spatial and morphological tissue context. BaseScopeTM is a novel in situ hybridization technology
that allows visualization of splice junctions between adjacent exons and/or retained introns in highly
specific and sensitive manner, allowing characterization of alternative splicing and circular RNAs in
cells and tissues.
