Oxford Events, the new replacement for OxTalks, will launch on 16th March. The two-week OxTalks freeze period starts on Monday 2nd March. During this time, there will be no facility to publish or edit events. The existing OxTalks site will remain available to view during this period. Once Oxford Events launches, you will need a Halo login to submit events. Full details are available on the Staff Gateway.
Multiple myeloma (MM) is characterized by accumulation of malignant plasma cells in the bone marrow, where tumor cells are in close contact with stromal fibroblasts. Using single cell RNA-sequencing we generated transcriptional maps of MM cells and their stromal and immune microenvironments. This revealed the presence of inflammatory stromal fibroblasts and bone marrow inflammation. I will discuss the identity of the MM stromal cells, their possible impact on MM disease progression and the interactions between inflammatory stromal cells and innate immune cells leading to a pro-tumor bone marrow environment.