OxTalks will soon move to the new Halo platform and will become 'Oxford Events.' There will be a need for an OxTalks freeze. This was previously planned for Friday 14th November – a new date will be shared as soon as it is available (full details will be available on the Staff Gateway).
In the meantime, the OxTalks site will remain active and events will continue to be published.
If staff have any questions about the Oxford Events launch, please contact halo@digital.ox.ac.uk
Abstract:
Human embryos are remarkably prone to mitotic errors during their first days of development: up to 70% carry genetically abnormal cells by the third day. In the first part of this seminar, I will cover the journey we all made from a chaotic genetic content to a (mostly) normal genome, summarizing what we know on how we manage this feat. In the second half, I will move on to human embryonic stem cells, the in vitro counterpart of the inner cell mass – the part of the embryo that becomes the fetus. Embryonic stem cells are also prone to genomic instability, which my lab studies from multiple angles. In this talk, I will present some of the work we do, and show you the opportunities these abnormalities provide to discover gene function in cell fate specification, during a window of human development otherwise inaccessible.
