On 28th November OxTalks will move to the new Halo platform and will become 'Oxford Events' (full details are available on the Staff Gateway).
There will be an OxTalks freeze beginning on Friday 14th November. This means you will need to publish any of your known events to OxTalks by then as there will be no facility to publish or edit events in that fortnight. During the freeze, all events will be migrated to the new Oxford Events site. It will still be possible to view events on OxTalks during this time.
If you have any questions, please contact halo@digital.ox.ac.uk
Abstract:
Human embryos are remarkably prone to mitotic errors during their first days of development: up to 70% carry genetically abnormal cells by the third day. In the first part of this seminar, I will cover the journey we all made from a chaotic genetic content to a (mostly) normal genome, summarizing what we know on how we manage this feat. In the second half, I will move on to human embryonic stem cells, the in vitro counterpart of the inner cell mass – the part of the embryo that becomes the fetus. Embryonic stem cells are also prone to genomic instability, which my lab studies from multiple angles. In this talk, I will present some of the work we do, and show you the opportunities these abnormalities provide to discover gene function in cell fate specification, during a window of human development otherwise inaccessible.