Oxford Events, the new replacement for OxTalks, will launch on 16th March. From now until the launch of Oxford Events, new events cannot be published or edited on OxTalks while all existing records are migrated to the new platform. The existing OxTalks site will remain available to view during this period.
From 16th, Oxford Events will launch on a new website: events.ox.ac.uk, and event submissions will resume. You will need a Halo login to submit events. Full details are available on the Staff Gateway.
Several decades after the first observation of DNA modifications in mammals, we still do not know why some DNA bases are modified and whether it really matters to begin with. Although there are only three DNA methyltransferases (DNMTs) and three DNA oxygenases (TETs), an infinite number of DNA modification patterns can be observed throughout development and disease. Over the past decades, several functional links with other epigenetic pathways and cellular metabolism have been described. In this talk, I will focus on the surprising and opposing roles of TET, UHRF1 and DPPA3 in the regulation of DNA modifications and pluripotency. I will present data on the pivotal role of ubiquitination in regulating DNA modifications, as well as new regulatory mechanisms.
