• Type: Seminar Series
• Series organisers: Anton van der Merwe (Sir William Dunn School of Pathology) , Chris Norbury (University of Oxford, Sir William Dunn School of Pathology, The Queen's College) , Fumiko Esashi (University of Oxford, Sir William Dunn School of Pathology, Weatherall Institute of Molecular Medicine) , Jo Peel (University of Oxford, Sir William Dunn School of Pathology) , Melissa Wright (Sir William Dunn School of Pathology)
• Organising department: Sir William Dunn School of Pathology

Friday 13 February 2015

• 14:00 - A new logic for polycomb chromatin domain formation
  Prof. Rob Klose (Department of Biochemistry, University of Oxford)

Friday 20 February 2015

• 14:00 - The E3 Ligase Listerin/Ltn1 links Co-translational Protein Quality Control and Neurodegeneration
  Prof. Claudio Joazeiro (The Scripps Research Institute)

Friday 27 February 2015

• 14:00 - Protecting our genomes against toxic metabolism
  Prof. K J Patel (MRC Laboratory of Molecular Biology, Cambridge)

Friday 6 March 2015

• 14:00 - NETs - the second function of chromatin
  Prof. Arturo Zychlinsky (Max Planck Institute for Infection Biology, Berlin)

Friday 13 March 2015

• 14:00 - A role for cohesin in regulating enhancer interactions and enhancer-proximal genes
  Prof. Matthias Merkenschlager (MRC Clinical Sciences Centre, London)

Friday 20 March 2015

• 14:00 - DNA strand break repair and links to human disease
  Prof. Stephen West (London Research Institute, Clare Hall Laboratories, Cancer Research UK)

Friday 27 March 2015

• 14:00 - Border patrol: regulation of membrane function and identity by ubiquitin dependent proteolysis
  Dr Pedro Carvalho (Centre for Genomic Regulation, Barcelona, Spain )

Friday 24 April 2015

• 14:00 - Pericentromeres and chromosome segregation in mitosis and meiosis
  Dr Adele Marston (Wellcome Trust Centre for Cell Biology, University of Edinburgh )

Friday 8 May 2015

• 14:00 - Conserved and non-conserved pathways underlying vertebrate limb regeneration
  Prof. Elly Tanaka (Technical University of Dresden, DFG Research Centre for Regenerative Therapies)

Friday 15 May 2015

• 14:00 - Sensing and Restricting: Innate immune control of HIV
  Dr Jan Rehwinkel (MRC Human Immunology Unit, WIMM, University of Oxford )

Friday 19 June 2015

• 14:00 - How to hit HIV where it hurts
  Professor Arup K Chakraborty (Departments of Chemical Engineering, Physics, Chemistry, and Biological Engineering, Institute for Medical Engineering and Science, MIT)

Friday 16 October 2015

• 14:00 - The collective cell biology of organ formation
  Dr Darren Gilmour (EMBL Heidelberg )

Friday 30 October 2015

• 14:00 - Species difference in ANP32A underlies influenza A virus polymerase host restriction
  Professor Wendy Barclay (Department of Medicine, Imperial College London )

Friday 6 November 2015

• 14:00 - Control of cell division by the PP2A-B55 pathway: basic principles really can be a matter of life and death
  Professor Francis Barr (Department of Biochemistry, University of Oxford )

Friday 13 November 2015

• 15:00 - Chaperone-assisted folding of the cystic fibrosis-related ABC-transporter CFTR
  Professor Ineke Braakman (Utrecht University )

Friday 20 November 2015

• 14:00 - Genome-embdedded ribonucleotides: in sickness and in health
  Professor Andrew Jackson (University of Edinburgh )

Friday 27 November 2015

• 14:00 - Cellular responses to DNA replication stress in yeast and in human cells
  Professor Philippe Pasero (Institute of Human Genetics, Montpeillier, France)

Friday 4 December 2015

• 14:00 - Lesson in viral pathogenesis from the barnyard
  Professor Massimo Palmarini (Director of centre for virus research, University of Glasgow)

Friday 18 December 2015

• 14:00 - Integrated analysis of anti-fungal innate immunity in C. elegans
  Dr Jonathan Ewbank (Centre d'Immunologie de Marseille-Luminy)

Friday 22 January 2016

• 14:00 - Complex multi-enhancer contacts captured in ES cells by Genome Architecture Mapping, a novel ligation-free approach
  Professor Ana Pombo (Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin)

Friday 5 February 2016

• 14:00 - Ubiquitin and Autophagy Networks in Health and Disease
  Professor Ivan Dikic (Goethe University School of Medicine)

Friday 19 February 2016

• 14:00 - Light, Sleep and Time: Neuroscience to therapeutics
  Professor Russell Foster (NDCN, University of Oxford )

Friday 26 February 2016

• 14:00 - The Type VII protein secretion system of Staphylococcus aureus
  Professor Tracy Palmer (University of Dundee )

Friday 11 March 2016

• 14:00 - HIV, DNA sensing and a new paradigm for antiviral therapeutics
  Professor Greg Towers (University College London )

Friday 18 March 2016

• 14:00 - Molecular mechanisms ensuring chromosome segregation
  Dr Julie Welburn (Wellcome Trust Centre for Cell Biology, University of Oxford )

Friday 13 May 2016

• 14:00 - Understanding Cellular Heterogeneity
  Dr Sarah Teichmann (Wellcome Trust Sanger Institute )

Friday 20 May 2016

• 14:00 - Salmonella diarrhea: inflammasome-driven disease, microbiota-interactions and fast phage traffic
  Professor Wolf-Dietrich Hardt (Institute of Microbiology (D-BIOL) ETH Zurich)

Thursday 26 May 2016

• 14:00 - Cytosolic anti-bacterial immunity: sensing & execution
  Dr Feng Shao (National Institute of Biological Sciences, Beijing, China )

Friday 10 June 2016

• 14:00 - The ER exit sites at the heart of cellular stress response
  Dr Catherine Rabouille (Hubrecht Institute, The Netherlands )

Friday 17 June 2016

• 14:00 - Microbial sensing in the malaria vector Anopheles gambiae
  Dr Elena Levashina (Max-Planck-Institut für Infektionsbiologie, Germany)

Friday 14 October 2016

• 14:00 - Epigenetic targeting during infection by Legionella pneumophila
  Professor Carmen Buchrieser (Biologie des Bactéries Intracellulaires, France)

Friday 28 October 2016

• 14:00 - Principle of Duality in Phospholipids: Regulators of Membrane Morphology and Dynamics
  Dr Banafshe Larijani (Basque Foundation for Science)

Friday 4 November 2016

• 14:00 - Chromosome silencing mechanisms in X chromosome
  Professor Neil Brockdorff (Department of Biochemistry, University of Oxford )

Friday 18 November 2016

• 14:00 - The true history of Penicillin: medicine's first spin story
  Dr Eric Sidebottom

Friday 2 December 2016

• 14:00 - Architecture of the eukaryotic replisome
  Dr Alessandro Costa (The Francis Crick Institute, London)

Friday 20 January 2017

• 14:00 - Centrosomes in development and disease: from control of spindle positioning to maintenance of genetic stability
  Dr Renata Basto (Institute Curie )

Friday 27 January 2017

• 14:00 - Targeting heterochromatin to safeguard the genome : how and why
  Professor Susan Gasser (University of Basel)

Friday 3 February 2017

• 14:00 - TULiPs from Tübingen: sorting flowers from weeds in intracellular lipid traffic
  Dr Tim Levine (Department of Cell Biology, UCL Institute of Opthalmology, London)

Monday 6 February 2017

• 10:30 - The establishment of new Shigella sonnei populations
  Professor Stephen Baker (OUCRU, Vietnam)

Friday 24 February 2017

• 14:00 - Reverse genetic screens in an intracellular malaria parasite: from cell fate decisions to genome evolution
  Dr Oliver Billker (Wellcome Trust Sanger Institute)

Friday 3 March 2017

• 15:00 - Crosstalk of innate immunity and cell death pathways in inflammatory diseases and cancer
  Professor Maya Saleh (McGill University)

Friday 17 March 2017

• 14:00 - The Immunity War of Elie Metchnikoff
  Luba Vikhanski (Weizmann Institute of Science, Rehovot)

Friday 24 March 2017

• 14:00 - RNA binding proteins play roles in B lymphocyte development, maintenance and activation
  Dr Martin Turner (Babraham Institute, Cambridge)

Friday 21 April 2017

• 14:00 - Comparative approach to understanding mitotic division
  Dr Snezhana Oliferenko (Kings College, London)

Friday 28 April 2017

• 13:00 - Beyond the bacterial paradigm in gene regulation
  Professor Jeremy Gunawardena (Harvard Medical School)

Friday 5 May 2017

• 14:00 - The centrosome duplication cycle: impact of centrosome aberrations on microcephaly and cancer
  Professor Erich A Nigg (University of Basel)

Friday 12 May 2017

• 14:00 - Triggering mitosis: DNA replication as an integral component of the cell-cycle engine
  Dr Arne Lindqvist (Karolinska Institute)

Friday 19 May 2017

• 14:00 - Role of the Microbiota in the control of immunity and inflammation
  Dr Yasmine Belkaid (National Institute of Health, NIAID, Bethesda USA)

Friday 9 June 2017

• 14:00 - Exploring Cancer’s addiction to deregulated G1/S cell cycle transcription
  Professor Robertus de Bruin (University College London)

Friday 16 June 2017

• 14:00 - Deciphering the Guidance Cue Code for B cell Immunity
  Professor Jason Cyster (University of California)

Tuesday 18 July 2017

• 14:00 - Activating inflammation
  Prof Adrian Liston (University of Leuven / VIB)

Friday 13 October 2017

• 14:00 - Aneuploidy in human cells: from Down's syndrome to cancer
  Dr Zuzana Storchova (Max Planck Institute of Biochemistry)

Friday 20 October 2017

• 14:00 - Caspase 3 initiates cell differentiation through targeted proteome and genome alterations
  Professor Lynn Megeney (Ottawa Hospital Research Institute)

Friday 27 October 2017

• 14:00 - How sensory neurons drive organ development and homeostasis– Drosophila models for hematopoiesis and immunity
  Dr Katja Brueckner (University of California)

Friday 3 November 2017

• 14:00 - Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to host signals
  Professor Petra Dersch (Helmholtz Centre for Infection Research)

Friday 17 November 2017

• 14:00 - Endothelial mechanobiology - going with the flow
  Professor Paul Evans (Sheffield University)

Friday 24 November 2017

• 14:00 - Conserved roles of Rif1 in Chromosome Maintenance
  Professor Anne Donaldson (University of Aberdeen)

Friday 1 December 2017

• 14:00 - Building a membrane on the other side of the wall
  Professor Thomas Silhavy (Princeton University)

Friday 19 January 2018

• 14:00 - Learning from helminths: Macrophage Dynamics in Type 2 immunity
  Professor Judith Allen (University of Manchester)

Friday 2 February 2018

• 14:00 - One step back, two steps forward: Toxin-antitoxin modules and persister formation of Escherichia coli
  Professor Kenn Gerdes (University of Copenhagen)

Friday 23 February 2018

• 14:00 - From lipid rafts to clinical lipidomics
  Professor Kai Simons (Max Planck Institute)

Friday 2 March 2018

• 14:00 - “Structural basis of long double-stranded RNA recognition by MDA5”
  Dr Yorgo Modis (University of Cambridge)

Friday 9 March 2018

• 14:00 - Fundamental physiology and target discovery in type 2 diabetes: Science at the interface of academia and pharma
  Professor James Johnson (University of British Columbia)

Friday 23 March 2018

• 14:00 - Not your average kinases - moonlighting functions of RAF and MEK in cancer and cell fate determination
  Professor Manuela Baccarini (University of Vienna)

Friday 4 May 2018

• 14:00 - The human antibody response in dengue and Zika virus infection
  Professor Gavin Screaton (University of Oxford)

Friday 11 May 2018

• 14:00 - Unconventional secretion and clearance of mutant SOD1 linked to amyotrophic lateral sclerosis
  Dr Vivek Malhotra (Centre for Genomic Regulation Barcelona)

Friday 18 May 2018

• 13:00 - Job’s dilemma for the genome: Why bad things happen to good chromosomes.
  Professor David Pellman (Harvard Medical School)

Friday 25 May 2018

• 13:00 - The role of non coding RNA in genome stability
  Dr Fabrizio d'Adda di Fagagna (IFOM)

Friday 1 June 2018

• 14:00 - How to engage with millions people
  Roger Highfield (University of Oxford)

Friday 8 June 2018

• 14:00 - Modulating T cell function for specific immunotherapy of autoimmune and allergic diseases
  Professor David Wraith (University of Birmingham)

Friday 15 June 2018

• 14:00 - Hypoxic Regulation of Lipid Metabolism: Lessons for Cancer from Yeast
  Professor Peter Espenshade (Johns Hopkins University)

Friday 22 June 2018

• 14:00 - Structural basis of long double-stranded RNA recognition by MDA5
  Dr Yorgo Modis (University of Cambridge)

Friday 6 July 2018

• 14:00 - L-form bacteria: antibiotics, lysozyme and chronic infection
  Professor Jeff Errington (Newcastle University)

Thursday 2 August 2018

• 14:00 - Studying innate immunity by vaccinia virus immune evasion strategies
  Professor Geoffrey L. Smith (University of Cambridge)

Friday 12 October 2018

• 14:00 - Studying innate immunity by vaccinia virus immune evasion strategies
  Professor Geoffrey L. Smith (University of Cambridge)

Friday 19 October 2018

• 14:00 - A Ring to Rule Them All: From Cell Polarity to Bacterial Virulence Control
  Professor Urs Jenal (University of Basel)

Friday 26 October 2018

• 14:00 - Taking a closer look at T cell fate decisions
  Professor Stephen Cobbold (University of Oxford)

Friday 2 November 2018

• 14:00 - Innate host defence: A playing field for the ubiquitin machinery
  Professor Mads Gryd-Hansen (Oxford Ludwig Institute)

Friday 9 November 2018

• 13:00 - Linking architecture and function of cellular membranes by correlative microscopy
  Professor Wanda Kukulski (University of Cambridge)

Friday 16 November 2018

• 14:00 - Mechanisms of recruitment and exchange of RNA polymerase II CTD factors
  Professor Richard Stefl (Central European Institute of Technology)

Friday 23 November 2018

• 14:00 - Buckling of an epithelium growing under spherical confinement
  Professor Aurelien Roux (University of Geneva)

Friday 30 November 2018

• 13:00 - Coping with a stressful start in life
  Professor Alex Gould (The Francis Crick Institute)

Friday 1 February 2019

• 14:00 - New concepts on targeting of proteins to organelles
  Professor Maya Schuldiner (Weizmann Institute of Science)

Friday 8 February 2019

• 14:00 - Modelling human brain development and connectivity in cerebral organoids
  Dr Madeline Lancaster (MRC Laboratory of Molecular Biology)

Friday 22 February 2019

• 14:00 - Structural insights into the targeting of tail-anchored membrane proteins to the ER
  Professor Bil Clemons (Caltech)

Friday 1 March 2019

• 14:00 - Accessory proteins harness the unique molecular architecture of the COPI vesicle coat
  Professor Blanche Schwappach (University Medical Center Gottingen)

Friday 15 March 2019

• 14:00 - Developments in Super-resolution Microscopy for Cell Biological Research
  Professor Joerg Bewersdorf (Yale University)

Thursday 21 March 2019

• 14:00 - From motility to signaling: The role of the cilium in Chlamydomonas
  Professor Susan Dutcher (Washington University)

Friday 29 March 2019

• 14:00 - New insights into viral immune evasion from quantitative multiplexed proteomics
  Dr Michael Weekes (University of Cambridge)

Friday 5 April 2019

• 14:00 - How chromatin is reorganized during zygotic reprogramming to totipotency
  Dr Kikue Tachibana-Konwalski (Institute of Molecular Biotechnology, Vienna)

Friday 3 May 2019

• 13:00 - Sympathetic neuroimmunity in Obesity
  Professor Ana Domingos (University of Oxford, DPAG)

Friday 10 May 2019

• 14:00 - Cancer immunity: creating the perfect storm
  Professor Awen Gallimore (Cardiff University)

Friday 24 May 2019

• 13:00 - Iron-sulfur clusters, essential actors for life
  Professor Frederic Barras (Centre national de la recherche scientifique, France)

Friday 31 May 2019

• 13:00 - Organelle contact sites: a new layer in the organization of Eukaryotic cells.
  Professor Benoit Kornmann (University of Oxford)

Friday 7 June 2019

• 14:00 - Regulating with RNA in pathogenic Epsilonproteobacteria
  Professor Cynthia Sharma (University of Wurzburg)

Friday 4 October 2019

• 14:00 - The Neural Stem Cell:Carnitine Malnutrition Hypothesis -- New Prospects For Effective Reduction Of Autism Risk?
  Professor Vytas Bankaitis (Texas A&M University)

Friday 11 October 2019

• 14:00 - Coupling neural fate determination with morphogenetic movements during zebrafish olfactory placode development
  Professor Patrick Blader (CBI, Toulouse)

Friday 18 October 2019

• 14:00 - Shaping of immunity by endogenous retroelements
  Professor George Kassiotis (The Francis Crick Institute, London)

Friday 25 October 2019

• 14:00 - A mechanism to reset mother centrioles before mitosis
  Professor Gislene Pereira (Centre for Organismal Studies, Heidelberg)

Friday 1 November 2019

• 14:00 - From Asymmetric Stem Cell Division To Tissue Engineering
  Dr Shukry Habib (Centre for Stem Cells & Regenerative Medicine, King's College London)

Friday 8 November 2019

• 13:00 - Lipodystrophy derived insights into the regulation of surplus and membrane lipids in adipocytes
  Professor David Savage (University of Cambridge)

Friday 15 November 2019

• 14:00 - New insights into bacterial chemoreceptor by cryo-electron tomography
  Professor Ariane Briegel (Leiden University)

Friday 22 November 2019

• 14:00 - Mechanisms of DNA processing machines - from transcription initiation to DNA damage repair
  Professor Xiaodong Zhang (Imperial College, London)

Friday 29 November 2019

• 14:00 - The Type VI Secretion System: A bacterial Killing Machine
  Professor Alain Filloux (Imperial College London)

Tuesday 17 December 2019

• 11:00 - To Build a Biofilm
  Professor George O'Toole (Dartmouth University)

Monday 13 January 2020

• 14:00 - Title TBC
  Professor Gia Voeltz (Univesity of Colorado, Boulder)

Friday 31 January 2020

• 14:00 - New Perspectives on Innate Lymphoid Cell Development and Function
  Professor James Di Santo (Institut Pasteur, France)

Friday 7 February 2020

• 14:00 - How T-Cells Recognize Antigens – Perspectives from Molecular Imaging
  Professor Johannes Huppa (Medical University of Vienna)

Friday 28 February 2020

• 14:00 - The structure and lifecycle of HIV-1 - new insights from cryo-electron tomography.
  Dr. John Briggs (MRC Cambridge)

Friday 6 March 2020

• 14:00 - Circadian regulation of the pulmonary immune response
  Professor David Ray (University of Oxford)

Friday 20 March 2020

• 14:00 - Mechanisms of Influenza virus uncoating by host factors
  This talk has been cancelled. Apologies for any inconvenience caused
  Dr Yohei Yamauchi (University of Bristol)

Friday 24 April 2020

• 14:00 - Regulation of microtubule organisation and dynamics: seeing proteins and drugs in action
  This talk has been cancelled. Apologies for any inconvenience caused
  Professor Anna Akhmanova (Utrecht University)

Friday 15 May 2020

• 14:00 - Environment control of T cell function
  Delivered via Zoom
  Professor Doreen Cantrell (Professor of Cell Biology and Immunology and Wellcome Trust Principal Research Fellow, University of Dundee)

Friday 22 May 2020

• 14:00 - Title TBC
  This talk has been cancelled. Apologies for any inconvenience caused
  Professor Melanie Blokesch (Global Health Institute, Switzerland)

Friday 29 May 2020

• 13:00 - Title TBC
  This talk has been cancelled. Apologies for any inconvenience caused
  Dr. Andrew Carter (MRC Laboratory of Molecular Biology, Cambridge)

Friday 5 June 2020

• 14:00 - Title TBC
  This talk has been cancelled. Apologies for any inconvenience caused
  Professor Simon Draper (University of Oxford)

Friday 12 June 2020

• 14:00 - Title TBC
  This talk has been cancelled. Apologies for any inconvenience caused
  Dr. Yanlan Mao (University College London)

Friday 19 June 2020

• 14:00 - Title TBC
  This talk has been cancelled. Apologies for any inconvenience caused
  Professor Gia Voeltz (Univesity of Colorado, Boulder)

Friday 3 July 2020

• 14:00 - Systems-wide analysis of ADP-ribosylation using quantitative mass spectrometry
  This talk has been cancelled. Apologies for any inconvenience caused
  Professor Michael Nielsen (Novo Nordisk Foundation, Copenhagen)

Friday 11 September 2020

• 15:00 - ER contact sites regulate the dynamics of membrane bound and membrane-less organelles
  WEBINAR - zoom link - https://zoom.us/j/96813570811?pwd=YkZTQURPRlg3eFFNcVp5a0R6QzduZz09
  Prof Gia Voeltz (HHMI and University of Colorado - Boulder)

Friday 25 September 2020

• 14:00 - Membrane protein biogenesis at the endoplasmic reticulum
  Zoom link - https://zoom.us/j/95934709943?pwd=a1FxWUYyZVJEdmhVbW9ZTFhJVFNjdz09
  Dr Ramanujan Hegde (Cell Biology Division, MRC Laboratory, Cambridge)

Friday 9 October 2020

• 14:00 - Neuropilin-1 promotes SARS-CoV-2 entry and spread by binding the furin-processed SARS-CoV-2 Spike and is a target for antiviral intervention
  https://zoom.us/j/95331996644?pwd=OWphQkM3K29aeVdzRzM4b29mU1VtZz09
  Dr Yohei Yamauchi (University of Bristol)

Friday 23 October 2020

• 14:00 - Understanding congenital diseases in relation to nuclear envelope dynamics
  Dr Christian Schlieker (Department of Cell Biology, Yale University)

Friday 6 November 2020

• 14:00 - Unravelling the structure of toxic protein aggregates in situ
  https://zoom.us/j/98323763786?pwd=VnN0NGtBckduV2huWk1WeGx3VVVkZz09
  Prof. Ruben Fernandez-Busnadiego (University of Göttingen Medical Center, Institute of Neuropathology)

Friday 13 November 2020

• 13:00 - Single-cell physiology of bacterial pathogens in rodent and human host tissues
  https://zoom.us/j/97385041140?pwd=b0d5M1ZCZG5MN3YrWTdHMDA2cmJ1QT09
  Prof Dirk Baumann (Biozentrum, University of Basel, Switzerland)

Friday 20 November 2020

• 14:00 - A mechanistic basis for modulating signalling by immune receptors
  https://zoom.us/j/92715812459?pwd=S0dyVmY5TitDYUJOdm81bDlaanNEdz09
  Dr Ricardo A Fernandes (Nuffield Department of Medicine and the Chinese Academy of Medical Sciences at Oxford Institute (CAMS/COI))

Friday 27 November 2020

• 14:00 - Coping with mechanical stress: tissue dynamics during growth and repair
  https://zoom.us/j/94992502579?pwd=c3lmOHBmMVI2b25rT084M2tlWTFiQT09
  Dr Yanlan Mao (UCL)

Friday 29 January 2021

• 14:00 - Pathoecology and evolution of Vibrio cholerae
  Zoom link: https://zoom.us/j/91760131201?pwd=bHdMUTVtN2VZVXlpd1VsMEd6RkRqZz09 Passcode: 565019 Webinar ID: 917 6013 1201
  Prof Melanie Blokesch (EPFL (Lausanne), Switzerland)

Friday 5 February 2021

• 14:00 - Development of Next-Gen Vaccines against the Blood-Stage Human Malaria Parasite
  ZOOM LINK: https://zoom.us/j/92997778356?pwd=VFVmdFlhWlZySWN4dXlteVVvNHcrdz09 Passcode: 441955 Webinar ID: 929 9777 8356
  Prof Simon Draper (Jenner Institute, University of Oxford)

Friday 12 February 2021

• 14:00 - Control of microtubule organisation and dynamics: seeing proteins and drugs in action
  ZOOM LINK: https://zoom.us/j/93298616588?pwd=YmJJMkYwKy9wVXR0NjZkOXZqWVFrUT09 Passcode: 351472 Webinar ID: 932 9861 6588
  Prof Anna Akhmanova (Life Sciences, Utrecht University, The Netherlands)

Friday 26 February 2021

• 14:00 - Policing secretion: quality control during export from the endoplasmic reticulum.
  Dr Liz Miller (MRC - LMB, Crick Institute, Cambridge)

Friday 5 March 2021

• 14:00 - E. coli persistence to ofloxacin
  Zoom Link https://zoom.us/j/92172459889?pwd=QTNMYkxudDFyNkpCNzVKWXN2U2J1dz09
  Prof Laurence Van Melderen (Université Libre de Bruxelles, Belgium)

Friday 12 March 2021

• 14:00 - Cancer evolution, immune evasion and metastasis
  ZOOM LINK https://zoom.us/j/95490025190?pwd=cFV5Nkd2bFR3SEkzTE9JeFV1WTlwZz09
  Prof Charles Swanton (The Francis Crick Institute, London)

Friday 19 March 2021

• 14:00 - Lung epithelia under attack: Infection, Interferon, Inflammation
  https://zoom.us/j/95308712651?pwd=Sm9lNVpPMjUvb3BXYXVWRXNQMUswUT09
  Dr Andreas Wack (The Francis Crick Institute, London)

Friday 26 March 2021

• 14:00 - Advanced Cell Therapy Designs Using Synthetic Biology
  https://zoom.us/j/98965906761?pwd=Ulh2MCtnd3JldEtUR0tVM3JxcVFKdz09
  Dr Wilson Wong (Department of Biomedical Engineering, Biological Design Center, Boston University)

Friday 23 April 2021

• 14:00 - Decoding the aneuploidy conundrum
  https://zoom.us/j/96016250156?pwd=NlZrQ2wrVjBEQVp5VFZ0Z052RFdjQT09
  Prof Rong Li (John Hopkins University, Maryland, USA)

Friday 7 May 2021

• 14:00 - Deconstructing a T3SS effector network unravels the inherent robustness and plasticity in pathogenesis and immunity
  https://zoom.us/j/98337177657?pwd=cURud3NVN3VTK1pFVER0REMrcFJwZz09
  Prof Gad Frankel (Imperial College, London)

Friday 14 May 2021

• 14:00 - Rewiring Cell Division
  https://zoom.us/j/97182989483?pwd=TXRnK1ZicmFDeWVuTHFZSGZjcXhHQT09
  Prof Iain Cheeseman (The Whitehead Institute, MIT, USA)

Friday 4 June 2021

• 14:00 - How has Salmonella become so dangerous in Africa?
  https://zoom.us/j/94552594140?pwd=QmliN2F5Sm53TEY5NHZiRjE1VlBQdz09
  Prof Jay Hinton (University of Liverpool)

Friday 11 June 2021

• 14:00 - Chromosome-membrane ensheathing: unwrapping a mitotic mystery
  https://zoom.us/j/94535031923?pwd=SDN0OTlvOHY4RXJza1pUNHplUGtKQT09
  Prof Steve Royle (University of Warwick)

Friday 9 July 2021

• 14:00 - A chromosome separation checkpoint
  https://us06web.zoom.us/j/91563720281?pwd=U1hmdWZYN1FhKyttdWJBRGhHSGdqQT09
  Prof Helder Maiato (Institute for Molecular and Cell Biology, University of Porto, Portugal)

Friday 10 September 2021

• 14:00 - Cell type-specific functions of mammalian centrosomes
  Dr Fanni Gergely (Biochemistry - University of Oxford)

Friday 17 September 2021

• 14:00 - Inspecting the secretory pathway with whole-cell, volumetric FIB-SEM
  https://us06web.zoom.us/j/97456211089?pwd=S1VFbEdnMnNuYTFUUmlnNGFvTy9kdz09
  Prof Jennifer Lippincott-Schwartz (HHMI - Janelia Research Campus, USA)

Friday 1 October 2021

• 14:00 - The importance of protection against formaldehyde in human physiology – From blood production to supressing cachexia and premature ageing’
  https://us06web.zoom.us/j/82648304156?pwd=aFNKOG44d3NsSFJwRHpjSHYzUHA2Zz09
  Prof K J Patel (WIMM, Oxford)

Friday 8 October 2021

• 14:00 - The evolutionary ecology of host defence and counter-defence
  https://us06web.zoom.us/j/86468144339?pwd=QTZ4K2swM2tPYzU2TlBVV0RRTG9jdz09
  Prof Edze Westra (University of Exeter)

Friday 5 November 2021

• 14:00 - Protein quality control at the endoplasmic reticulum
  https://us06web.zoom.us/j/82123734298?pwd=TnNtejBic3l4aW1DVHZwZEYwVldWUT09
  Dr Yihong Ye (NIDDK, NIH)

Friday 25 February 2022

• 14:00 - Genome-led vaccine target discovery for parasitic infections
  https://us06web.zoom.us/j/81828509326?pwd=TWRkVEg0NmxORlJYbW5GZ3lTVExyQT09
  Prof Gavin Wright (University of York)

Friday 11 March 2022

• 14:00 - Chromosome and Chromatin Dynamics at DNA Double Strand break
  https://us06web.zoom.us/j/88509904291?pwd=NGFmcXBzTTNneStUamFqa1JBdlB4Zz09
  Prof Gaelle Legube (CNRS - University of Toulouse)

Friday 22 April 2022

• 14:00 - Decoding and reprogramming immunity
  This will also be presented in a hybrid format - zoom link : https://us06web.zoom.us/j/84906011491?pwd=NDdmY1dDZUwwSU1FamdWVlMvcXNnQT09
  Prof Michael Birnbaum (MIT, USA)

Friday 6 May 2022

• 14:00 - Function of junk: satellite DNA in cell biology and speciation
  https://us06web.zoom.us/j/87321894183?pwd=VWpHbEU2N1dRdVRCTlUvSStYZ2RTZz09
  Dr Yukiko Yamashita (MIT, USA)

Wednesday 11 May 2022

• 14:00 - Transcriptional Regulatory Mechanisms in Hematopoietic Malignancies
  This will also be presented in a hybrid format - zoom link - https://us06web.zoom.us/j/84394658821?pwd=VkIwNlc0K3EwTmZSZHNmQk9hNXBRZz09
  Prof Rob Roeder (Rockefeller University, USA)

Friday 27 May 2022

• 13:00 - Small but powerful: The human vault RNAs as multifaceted modulators of pro-survival characteristics and tumorigenesis
  This will also be presented in a hybrid format - zoom link - https://us06web.zoom.us/j/82600760837?pwd=bVB4N01NZ3I5aG1abWpVL2F0V2xvZz09
  Dr Norbert Polacek (Universitat Bern)

Friday 10 June 2022

• 14:00 - The ties that bond: Unmasking the biofilm potential of the gut symbiont Bacteroides thetaiotaomicron
  This will also be presented in a hybrid format - zoom link - https://us06web.zoom.us/j/85215368752?pwd=c1YwbUdQNFhuL09kVGxJWENUREVrQT09
  Prof Jean-Marc Ghigo (Institut Pasteur, Paris)

Friday 17 June 2022

• 14:00 - Evolution of Epigenetic Regulation: A new cost for DNA methylation
  No longer hybrid format.
  Prof Peter Sarkies (Biochemistry, University of Oxford)

Friday 9 September 2022

• 14:00 - Mechanism of centromere recognition by regional and point kinetochores from structures of the human and budding yeast inner kinetochore complexes
  IN PERSON ONLY - NO LONGER OFFERING HYBRID FORMAT
  Prof David Barford (MRC - Cambridge)

Friday 23 September 2022

• 14:00 - The tubulin code: a molecular mechanism to coordinate complex cellular functions
  Prof Carsten Janke (Institut Curie, Paris)

Friday 7 October 2022

• 14:00 - Overriding MHC class I antigen presentation
  CANCELLED - DO NOT ATTEND
  Prof Louise Boyle (University of Cambridge)

Friday 14 October 2022

• 14:00 - Nuclear envelope remodelling during cell division and cell migration
  Prof Jeremy Carlton (Kings College, London)

Friday 21 October 2022

• 14:00 - UBIAD1, a vitamin K synthetic enzyme and regulator of proteostasis in cholesterol synthesis
  Prof Russell DeBose-Boyd (UTSouthwestern, USA)

Friday 28 October 2022

• 14:00 - Competition and warfare in bacteria: from model systems to the microbiome
  Prof Kevin Foster (Dept of Biology, University of Oxford)

Friday 4 November 2022

• 14:00 - Investigating the interplay between transcription control and replication stress
  Dr Eva Petermann (University of Birmingham)

Friday 11 November 2022

• 14:00 - Programming cell fate decisions by mitochondrial proteolysis
  Prof Thomas Langer (Maz Planck Institute, Germany)

Friday 18 November 2022

• 14:00 - Polarized secretion from killer cells
  Prof Gillian Griffiths (University of Cambridge)

Wednesday 23 November 2022

• 12:00 - ER remodelling via ER-phagy
  Prof Ivan Dikic (Goethe University Medical Faculty, Frankfurt)

Friday 25 November 2022

• 14:00 - Role of RNA in DNA repair and chromatin structure
  Prof Marianne Farnebo (Karolinska Institutet, Stockholm)

Friday 2 December 2022

• 14:00 - SARS-CoV-2: Translating science to public health impacts
  Prof Leo Poon (School of Public Health, The University of Hong Kong.)

Friday 27 January 2023

• 14:00 - From CRISPR biology to versatile technologies
  Prof. Dr. Chase Beisel (Helmholtz Center for Infection Research, University of Würzburg)

Friday 3 February 2023

• 14:00 - Recent work on immune receptor signalling
  Prof Simon Davis (MRC Weatherall Institute of Molecular Medicine, University of Oxford)

Friday 10 February 2023

• 14:00 - When viral RNA met the cell: a story of protein-RNA interactions
  Prof Alfredo Castello (University of Glasgow)

Friday 17 February 2023

• 14:00 - Population genomics of the meningococcus: insights and applications
  Prof Martin Maiden (University of Oxford)

Friday 24 February 2023

• 14:00 - Replenishing the ends: Visualisation of human telomerase by cryo-EM
  Dr Kelly Nguyen (MRC, Cambridge)

Friday 3 March 2023

• 13:00 - Overriding MHC class I antigen presentation
  NOTE - time change - starts at 1pm
  Prof Louise Boyle (University of Cambridge)

Friday 10 March 2023

• 14:00 - PBAF takes centre stage: chromatin remodelling at centromeres prevents mitotic instability
  Prof Jessica Downs (ICR, London)

Friday 24 March 2023

• 14:00 - The Journey towards Net-Zero Science
  Mr Martin Farley (UCL)

Friday 28 April 2023

• 13:00 - Ubiquitin chains as regulators of immune signalling and inflammation
  NOTE - Time change - starts at 1pm
  Prof Mads Gyrd-Hansen

Friday 5 May 2023

• 14:00 - The Extraordinary Life and Legacy of Sir John C. Kendrew
  Prof Paul M Wassarman (Icahn School of Medicine at Mount Sinai)

Friday 12 May 2023

• 14:00 - Asexuality, migration and genetic networks in regenerating flatworms
  Prof Aziz Aboobaker (Dept of Biology, University of Oxford)

Friday 2 June 2023

• 14:00 - Redefining mobility in bacterial genetics and its impact on infectious disease
  Prof Jose Penades (Imperial College, London)

Friday 9 June 2023

• 14:00 - Conserved mechanisms amidst diversity in segmented negative-strand RNA virus polymerases
  Dr Stephen Cusack, (EMBL, Grenoble)

Friday 16 June 2023

• 14:00 - Progress Towards Establishing Computational Microbiology: A Focus on Bacterial Cell Envelopes
  Prof Syma Khalid (Dept of Biochemistry, University of Oxford)

Friday 23 June 2023

• 14:00 - Hyperactive Protein Responses and Functional Residuomics of Cilia
  Status: This talk has been cancelled
  Prof Guangshuo Ou (Tsinghua University, Beijing, China)

Friday 7 July 2023

• 14:00 - Phases of fat: dissecting the life-cycle and biophysical phases of lipid droplets
  Prof Mike Henne (UT, Southwestern)

Friday 22 September 2023

• 14:00 - Meiotic DNA breaks drive multifaceted mutagenesis in the human germline
  Post seminar tea, coffee and biscuits will be available in the Combination Room.
  Dr Anjali Hinch (University of Oxford)

Friday 29 September 2023

• 14:00 - Transposons: from molecular mechanisms to the clinic
  Prof David Grainger (University of Birmingham)

Friday 13 October 2023

• 14:00 - Folding and assembly of membrane proteins
  Prof Manu Hegde (University of Cambridge)

Friday 27 October 2023

• 14:00 - Where, when and how: Spatial control of mitosis
  Prof Jon Pines (ICR, London)

Friday 3 November 2023

• 14:00 - Transcriptomics in infectious diseases- Biomarkers & Biology
  Prof Mahdad Noursadeghi (UCL)

Friday 10 November 2023

• 14:00 - Epigenetics and inheritance
  Prof Amanda Fisher (Dept of Biochemistry - University of Oxford)

Friday 17 November 2023

• 14:00 - Enabling discovery by in-cell structural biology
  Prof Julia Mahamid (EMBL, Germany)

Friday 24 November 2023

• 14:00 - Unravelling virus replication-induced organelle remodelling by cellular cryo-electron tomography
  Dr Petr Chlanda (Schaller Research Group Department of Infectious Diseases - Virology Heidelberg University Hospital)

Friday 1 December 2023

• 14:00 - Mitochondria-microbe conflict
  Prof Lena Pernas (MPI for Bio Ageing, Germany)

Friday 23 February 2024

• 14:00 - Anti-Viral Restriction at Cell Membranes
  Prof Michael Malim (Kings College, London)

Friday 1 March 2024

• 13:00 - Phase separation in cell physiology and disease
  THIS LECTURE HAS BEEN CANCELLED !!
  Prof Tony Hyman (Max Planck Institute of Molecular Cell Biology & Genetics)

Friday 12 April 2024

• 14:00 - From molecular mechanisms to policy: Neisseria gonorrhoeae as a roadmap to address AMR
  Dr Yonatan Grad (Department of Immunology and Infectious Diseases - Harvard T.H. Chan School of Public Health)

Friday 19 April 2024

• 14:00 - Hyperactive Protein Responses and Functional Residuomics of Cilia
  Prof Guangshuo Ou (Tsinghua University, Beijing, China)

Friday 26 April 2024

• 13:00 - Watching Amyloid Form: Structural Insights and New Opportunities for Intervention in Disease
  PLEASE NOTE - THIS LECTURE STARTS AT 1PM
  Prof Sheena Radford (University of Leeds)

Friday 3 May 2024

• 13:00 - The ups and downs of TGF-β family signalling
  PLEASE NOTE - EARLIER TIME OF 1PM
  Prof Caroline Hill (Francis Crick Institute, London)

Friday 10 May 2024

• 13:00 - The Type VI secretion system of Serratia marcescens and bacterial arms races
  PLEASE NOTE - EARLIER TIME OF 1PM
  Prof Sarah Coulthurst (University of Dundee)

Friday 17 May 2024

• 13:00 - The Biology of Proteostasis in Health, Aging and Disease
  PLEASE NOTE - EARLIER TIME OF 1PM
  Prof Rick Morimoto (Northwestern University)

Friday 24 May 2024

• 13:00 - How mRNA nuclear export allows you to live with a genome filled with junk DNA
  PLEASE NOTE - EARLIER TIME OF 1PM
  Prof Alexander Palazzo (University of Toronto)

Friday 7 June 2024

• 14:00 - Rare Disease Patient-Led Functional Genomics- A Tale of Tubulins
  Dr Pleasantine Mill (University of Edinburgh)

Friday 14 June 2024

• 14:00 - Does Cdk order the cell cycle, and what does life look like without loop extrusion?
  Prof Frank Uhlmann (The Francis Crick Institute, London)

Friday 5 July 2024

• 14:00 - Dissecting ubiquitin-mediated control of autophagy
  Prof Christian Behrends (LMU Germany)

Friday 13 September 2024

• 14:00 - From dendritic cells to inflammatory bowel disease
  Prof Simon Milling (University of Glasgow)

Friday 27 September 2024

• 14:00 - The ins and outs of cellular quiescence
  Dr Alexis Barr (Imperial College, London)

Friday 4 October 2024

• 14:00 - Characterising human proteome diversity in health and disease
  Prof Angus Lamond (University of Dundee)

Friday 11 October 2024

• 14:00 - Evolutionary cell biology of mitosis
  Prof Gautam Dey (EMBL)

Friday 18 October 2024

• 13:00 - Formation and function of the nuclear envelope
  NOTE TIME CHANGE TO 1pm
  Dr Shirin Bahmanyar (Yale University, USA)

Friday 1 November 2024

• 13:00 - Mapping DNA replication stress in cancer cells and parasites with long-read sequencing and AI
  PLEASE NOTE TIME CHANGE
  Dr Michael Boemo (University of Cambridge)

Friday 8 November 2024

• 13:00 - Measure once, cut twice: Regulating meiotic recombination at different spatial scales
  CANCELLED !!!!!!!
  Status: This talk has been cancelled
  Prof Matt Neale (University of Sussex)

Friday 22 November 2024

• 14:00 - Policing secretion: how the COPII coat directs specificity in export from the ER.
  Prof Liz Miller (MRC, Cambridge)

Friday 29 November 2024

• 14:00 - Disarm and disengage: Understanding Aurodox - a Type III Secretion System inhibitor from Streptomyces
  Prof Paul Hoskisson (University of Strathclyde)

Friday 31 January 2025

• 14:00 - Revisiting the neoantigen approach to cancer immunotherapy
  Prof Yardena Samuels (The Weizmann Institute of Science)

Friday 14 February 2025

• 14:00 - Designing and translating new bioengineering approaches for early disease detection and treatment
  Prof Molly Stevens (DPAG, Uni of Oxford)

Friday 21 February 2025

• 14:00 - Genetic and epigenetic organisation of plant centromeres
  Prof Ian Henderson (University of Cambridge)

Friday 28 February 2025

• 13:00 - Feedback control of mitosis in the context of the kinetochore
  NOTE TIME CHANGE!
  Prof Andrea Musacchio (Max Planck, Germany)

Friday 28 March 2025

• 14:00 - TBC
  Prof Ross Chapman (NDM - University of Oxford)