Dunn School of Pathology Research Seminars

These are occasional research seminars hosted by the Sir William Dunn School of Pathology. Seminar organisers who want to advertise a seminar should contact one of the list managers (see below). All are welcome.

Type: Seminar Series
Series organisers: Anton van der Merwe (Sir William Dunn School of Pathology) , Omer Dushek (University of Oxford, Sir William Dunn School of Pathology, Wolfson College) , Jo Peel (University of Oxford, Sir William Dunn School of Pathology) , Melissa Wright (Sir William Dunn School of Pathology)
Organising department: Sir William Dunn School of Pathology

Wednesday 17 June 2015

Monday 22 June 2015

14:00 - Themis and PKCeta in regulation of TCR signaling and Treg activity
Status: This talk is in preparation - details may change
Prof Nicholas R J Gascoigne (Dept of Microbiology, National University of Singapore)

Wednesday 1 July 2015

13:00 - The T-cell antigen receptor: The immune systems ultimate disease detection system?
Dr David Cole (Cardiff University)

Wednesday 8 July 2015

13:00 - Immune recognition à la physicienne
Professor Paul Francois (McGill University)

Wednesday 15 July 2015

13:00 - IDENTIFICATION OF CELL SURFACE RECEPTORS THAT ARE ESSENTIAL FOR SPERM-EGG RECOGNITION IN MAMMALS AND ERYTHROCYTE INVASION BY THE MALARIA PARASITE: METHODS, CELL BIOLOGY AND PRACTICAL APPLICATIONS
Dr Gavin Wright (Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge)

Monday 3 August 2015

11:00 - The initiation of DNA replication: detail of the reaction and its relationship between chromatin’
Dr Seiji Tanaka (National Institute of Genetics, Japan)

Wednesday 16 September 2015

13:00 - Cellular signalling in T cells is captured by a modular phenotypic model
Omer Dushek (University of Oxford, Sir William Dunn School of Pathology, Wolfson College)

Wednesday 30 September 2015

16:00 - Cancer vaccines in the era of successful immunotherapies
Professor Pedro Romero (Ludwig Center for Cancer Research, University of Lausanne)

Thursday 1 October 2015

13:00 - Herpesvirus infection causes a breakdown in transcriptional termination across host genome: high resolution gene expression profiling
Professor Lars Dolken (Institut fur Virologie und Immunbiologie, Wurzburg)

Thursday 8 October 2015

14:00 - Genome Editing Comes of Age – Lessons learned from high throughput CRISPR targeting in human cell lines
Chris Thorne (Horizon Discovery)

Wednesday 18 November 2015

13:00 - Mousematical modelling of Francisella tularensis infection
Dr Thomas Laws (DSTL), Dr Joseph Gillard (DSTL)

Wednesday 2 December 2015

Wednesday 20 January 2016

11:00 - Genome editing in stem cells, animals and plants
Professor Jin-Soo Kim (Seoul National University )

Thursday 11 February 2016

11:00 - Aberrant phase transitions in cytoplasm: implications for neurodegeneration
Professor Tony Hyman (Max Planck Institute of Molecular Cell Biology and Genetics)

Tuesday 1 March 2016

10:30 - Mechanisms of Tankyrase Function in Signal Transduction
Dr Sebastian Guettler (The Institute of Cancer Research, London)

Monday 7 March 2016

Thursday 10 March 2016

14:30 - The Drug Discovery challenges to eliminate malaria
Dr Jeremy Burrows (VP, Head of Drug Discovery, Medicines for Malaria Venture)

Friday 1 April 2016

14:00 - Computational modeling of cell decision processes
James Faeder (University of Pittsburgh)

Tuesday 3 May 2016

11:00 - The Penicillin case. The history of antibiosis before and after Lord Florey
Dr Giovanni Savignano (G. Moscati Hospital, Avellino, Italy)

Wednesday 4 May 2016

13:00 - Functional plasticity of CD4 T cells is driven by an asymmetric inheritance of mitochrondria
Professor Stephen Cobbold (University of Oxford)

Wednesday 11 May 2016

13:00 - Vascular Mechanotransduction: a journey from the protein to the vessel
Dr Ellie Tzima (Cardiovascular Medicine, Radcliffe Department of Medicine)

Friday 13 May 2016

11:00 - Real-time analysis of Rad51-mediated DNA strand exchange
Prof Hiroshi Iwasaki (Tokyo Institute of Technology, Japan )

Wednesday 18 May 2016

16:00 - From fitness comparison to spatial constrains: the many roads of cell competition
Dr Romain Levayer (Institute for Cell Biology, University of Bern, Switzerland )

Monday 6 June 2016

14:00 - 2D analysis of TCR-pMHC interaction reveals differential cell fate governed by tissue compartmentalization
Prof Cheng Zhu (Georgia Institute of Technology, Atlanta, Georgia)

Monday 20 June 2016

Monday 4 July 2016

11:00 - The Role of Promoter DNA Topology In Actively Transcribing Genes
Dr Hans Elmlund (Monash University, Australia)

Thursday 14 July 2016

11:00 - Single-cell genomics to study DNA-mutation, genetic heterogeneity and disease
Prof Thierry Voet (Associate Professor at the University of Leuven, Belgium & Associate Faculty Member, Wellcome Trust Sanger Institute)

Tuesday 19 July 2016

15:00 - Regulation of signal strength through the T cell receptor
Professor Nick Gascoigne (Professor and Head, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine :: National University of Singapore )

Tuesday 13 September 2016

15:00 - Spatial and dynamic control of T cell activation
Prof Bjorn Lillemeier (Nomis Center for Immunobiology and Microbial Pathogenesis Waitt Advanced Biophotonics Center The Salk Institute)

Friday 16 September 2016

14:00 - Regulation of microtubule end dynamics
Prof Gohta Goshima (Division of Biological Science Graduate School of Science, Nagoya University, Japan)

Monday 19 September 2016

14:00 - Host cellular reprogramming induced by dengue virus infection
Dr Sumana Sanyal (HKU - Pasteur Research Pole)

Wednesday 28 September 2016

11:00 - mTORC1 Controls Ribosome Production via LARP1
Dr Bruno Fonseca (Children's Hospital of Eastern Ontario Research Institute, Ottawa)

Monday 3 October 2016

13:00 - RNA Editing Enzyme Machines
Professor Ruslan Afasizhev (Boston University )

Tuesday 4 October 2016

15:00 - The power of high content imaging and screening in addressing DNA damage stress response
Dr Velibor Stavic (Genome Damage and Stability Centre, University of Sussex )

Friday 7 October 2016

14:00 - Novel activation mechanism of macromolecular complex APC/C ubiquitin ligase
Dr Hiro Yamano (UCL Cancer Institute)

Monday 17 October 2016

11:00 - Chromatin, PolII elongation and DNA damage regulate alternative splicing.
Prof Alberto Kornblihtt

Wednesday 19 October 2016

13:00 - Effector and memory CD8+ T cell fate decisions.
Professor Aymen Al-Shamkhani (Professor in Immunology, University of Southampton.)

Thursday 27 October 2016

11:00 - Bat influenza viruses: from sequences to replicating viruses
Dr Étori Aguiar Moreira (University of Freiburg)

Wednesday 2 November 2016

13:00 - Quantification of single-molecule super-resolution microscopy data of the T cell immunological synapse
Dr Dylan Owen (Experimental Biophysics & Nanotechnology, Kings College, London)

Tuesday 15 November 2016

11:00 - The enigmatic role of lipids in membrane protein organization
Dr Gerhard J.Schuetz (Institute of Applied Physics, TU Wien, Vienna, Austria)

Wednesday 16 November 2016

13:00 - Engineering T cell Specificity and Function for Cancer Therapy.
Prof Hans Stauss (Professor of Tumour Immunology, UCL)

Wednesday 30 November 2016

15:00 - HLA class I degradation by cytomegalovirus: uncovering novel features of ER-associated protein degradation using genetic screens
Mike van de Weijer (Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands)

Thursday 1 December 2016

11:30 - TERT Hypermethylated Oncologic Region - THOR: a new epigenetic cancer biomarker
DR Pedro Castelo-Branco (Department of Biomedical Sciences and Medicine, University of Algarve)

Monday 5 December 2016

14:00 - Transmission of signals across cell membranes: Elucidating the integrin and T-cell receptor activation mechanism via multi-scale simulations.
Dr Antreas Kalli (Leeds Institute of Cancer and Pathology, St James's University Hospital, University of Leeds)

Tuesday 13 December 2016

12:00 - Nuclear RNA surveillance
Professor Torben Jensen (Centre for mRNP Biogenesis and Metabolism, Aarhus University, Denmark)

Wednesday 14 December 2016

14:30 - Physiological role and optogenetic modulation of the transcription factor REST/NSRF in the nervous system
Prof Fabio Benfenati (Professor of Neurophysiology, Center for Synaptic Neuroscience and Technology, The Italian Institute of Technology)

Tuesday 10 January 2017

11:00 - Hsp90 supports a critical folding step of the ABC transporter CFTR
Daniel Fonseca (Utrecht University, The Netherlands)

Wednesday 11 January 2017

13:00 - TCR signal strength regulates Akt substrate specificity to induce alternate Th and Treg differentiation programs
Prof Penny Morel (Professor of Immunology, Department of Immunology, University of Pittsburgh)

Wednesday 18 January 2017

13:00 - 'Adaptive stress surveillance’ – a new paradigm in human gamma delta T cell biology ?
Prof Ben Willcox (Professor of Molecular Immunology, University of Birmingham)

Wednesday 25 January 2017

16:30 - The homologous recombination machinery & the DNA damage checkpoint co-ordinate chromosome mobility in diploid S. cerevisiae
****PLEASE NOTE CHANGE OF VENUE AND TIMINGS****
Prof Rodney Rothstein (Dept. Genetics & Development, Columbia University )

Wednesday 1 March 2017

13:00 - How T-cells recognize antigens - an imaging approach
Dr Johannes Huppa (Institute for Hygiene and Applied Immunology, Immune Recognition Unit, Medical University of Vienna)

Wednesday 15 March 2017

13:00 - Regulation of CD4 T cell activation and differentiation by CTLA-4
Prof Lucy Walker (Institute of Immunity & Transplantation, UCL Division of Infection & Immunity)

Thursday 23 March 2017

14:30 - The power of Single Cell Genomics: Discovery and Characterisation of novel human Immune Cells
Dr Chloe Villani (Fellow at the Broad Institute of MIT & Harvard and Harvard Medical School)

Monday 10 April 2017

15:00 - DNA methylation restrains effector functions in immune cells
Dr Silvia Monticelli (Institute of Biomedical Research (IBR) - Bellinzona (Switzerland) )

Wednesday 19 April 2017

15:00 - Signals that control growth and patterning
Dr Jean-Paul Vincent (Francis Crick Institute, London)

Tuesday 25 April 2017

16:00 - Genome-Wide Organization of DNA Replication
Prof Nick Rhind (University of Massachusetts Medical School)

Friday 28 April 2017

11:00 - Assessing costimulation and coinhibition in human T cells
Prof Peter Steinberger (Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna)

Friday 26 May 2017

13:00 - 'When MAITs matter – microbial defence and drug modulation’
Dr Sidonia Eckle (The Peter Doherty Institute for Infection and Immunity, Melbourne)

Tuesday 20 June 2017

11:30 - Leishmania genome instability as driver for fitness gain in the field and in culture
Dr Gerald Spaeth (Institut Pasteur)

Wednesday 21 June 2017

13:00 - New Insights into Immunology Revealed by Single Molecule Localization Microscopy
Dr Stefan Balint (NDORMS, Oxford)

Wednesday 5 July 2017

13:00 - Cell trafficking via lymph – interesting roles for a monotonous polysaccharide
Prof David G Jackson (WIMM, Oxford)

Thursday 6 July 2017

11:00 - The role of sugars in HIV neutralizing antibody sensitivity and vaccine development
Professor James Binley (San Diego Biomedical Research Institute, CA)

Thursday 14 September 2017

15:00 - Dynamics of Cell Migration, Tissue Morphogenesis, and Cancer
Prof Ken Yamada (NIH Distinguished Investigator, Chief, Laboratory of Cell and Developmental Biology, Head, Cell Biology Section)

Thursday 21 September 2017

11:00 - Genetic Control of Apoptosis-induced Proliferation in Drosophila
Dr Andreas Bergmann (University of Massachusetts Medical School)

Tuesday 26 September 2017

11:00 - Glioblastoma network deplete neuronal wg and induces neurodegeneration
Dr Sergio Casas-Tinto (Institute Cajal de Madrid)

Thursday 28 September 2017

15:00 - Role in cell-membrane organization of protein-protein interactions mediated by the membrane
Prof. Nicolas Destainville (Université Toulouse III-Paul Sabatier/CNRS)

Friday 29 September 2017

Tuesday 3 October 2017

14:00 - Digestion-Ligation-Only Hi-C: a simple, cost-effective, and highly efficient method for Chromosome Conformation Capture
Dr Guoliang Li (Huazhong Agricultural University, Wuhan, China)

Thursday 9 November 2017

14:15 - Mechanisms of trinucleotide repeat induced epigenetic instability
Dr Sasa Svikovic (MRC LMB, Cambridge)

Wednesday 15 November 2017

13:00 - Optical control of T-cell signalling dynamics
Dr John James (Cambridge Immunology Network / MRC Laboratory of Molecular Biology)

Thursday 16 November 2017

15:00 - Trust None of What You Hear and Less of What You See: Living with Caspases and Dying Without Them
Prof Eli Amara (Weizmann Institute of Science)

Wednesday 22 November 2017

Monday 27 November 2017

15:00 - Structures and functions of membrane interacting proteins using NMR, lipid screens and polymer-based nanodiscs.
Prof Michael Overduin (University of Alberta, Edmonton, Canada)

Wednesday 13 December 2017

13:00 - Collective T cell decisions during immune responses
Dr Audrey Gérard (University of Oxford)

Wednesday 20 December 2017

13:00 - Decoding the functional roles of genetic variants in complex phenotypes
Dr Justin O'Sullivan (Liggins Institute, University of Auckland, New Zealand)

Wednesday 10 January 2018

13:00 - Small proteins with big roles.
Dr Andrea Pauli (IMP Vienna, Austria)

Tuesday 16 January 2018

15:00 - Life without DNA replication origins – Is there a minimum size limit for recombination-dependent DNA replication?
Prof Thorsten Allers (University of Nottingham)

Wednesday 17 January 2018

13:00 - Understanding and manipulating the T-cell response to peptide-MHC
Prof Linda Wooldridge (Chair in Translational Immunology, University of Bristol)

Thursday 18 January 2018

11:00 - At the intersection of chromatin structure, transcription and DNA repair.
Dr Sergio de Almeida (iMM Lisbon, Portugal)

Wednesday 24 January 2018

13:00 - Discovering and re-discovering human memory T cell differentiation by high-dimensional single cell analysis
Dr Enrico Lugli (Humanitas Clinical and Research Center, Italy)

Tuesday 6 February 2018

10:00 - Using a light-activatable TCR to study signalling dynamics in T cells
Prof Wolfgang Schamel (BIOSS Centre for Biological Signalling Studies, University of Freiburg)

Tuesday 20 February 2018

11:00 - Mitosis, genome stability and cancer chemotherapy
Prof Stephen Taylor (Division of Cancer Sciences, University of Manchester)

Wednesday 21 February 2018

13:00 - Structure and mechanism of MHC I chaperone and peptide-loading complexes illuminate the onset of adaptive immunity
Professor Robert Tampé (Goethe University Frankfurt)

Thursday 1 March 2018

11:00 - Poly(ADP-ribosyl)ation-induced chromatin relaxation at the sites of DNA damage
Dr Gyula Timinszky (Institute of Genetics, Biological Research Centre of the Hungarian Academy of Sciences, Szeged)

Wednesday 7 March 2018

13:00 - Coincidence detection tailors macrophage responses to inflammatory signals
Dr Jelena Bezbradica (NDORMS, Oxford)

Wednesday 21 March 2018

11:00 - These go up to eleven: molecular counting of RNA segments in dsRNA viruses
Dr Alexander Borodavka (School of Molecular and Cellular Biology, University of Leeds)

Wednesday 4 April 2018

13:00 - Functional relevance and cancer related changes of protein post-translation regulation
Dr Pedro Beltrao (EMBL-EBI, Cambridge)

Friday 6 April 2018

15:00 - Model-based local density sharpening of cryo-EM maps
Prof Arjen Jakobi (TU Delft, The Netherlands )

Wednesday 25 April 2018

15:00 - Building a machine for secretion of bulky collagens from the endoplasmic reticulum
Dr Ishier Raote (CRG, Barcelona)

Thursday 26 April 2018

15:00 - Building Basement Membranes: Secretion, Assembly and Role in Tissue Growth
Dr Jose Pastor-Pareja (School of Life Sciences, Tsinghua University)

Wednesday 2 May 2018

13:00 - How do chemokines work? Combining experimental and computational approaches to determine how morphogens work
Dr Mark Coles (NDORMS, Oxford)

Wednesday 16 May 2018

15:00 - A dynamic contractile actomyosin network in cells that change behaviour during Drosophila morphogenesis
Dr Marcus Bischoff (Biomedical Sciences Research Complex, University of St Andrews)

Wednesday 6 June 2018

13:00 - Exploiting protein engineering to gain mechanistic insight into cytokine biology
Dr Ignacio Moraga (Principal Investigator, Dundee University)

Thursday 7 June 2018

10:00 - Structural studies of microbial self-defence mechanisms
Dr Ditlev Brodersen (Associate Professor, Department of Molecular Biology and Genetics, Aarhus University, Denmark)

Thursday 14 June 2018

15:00 - Maintenance of CD4 T effector function under glucose restriction
Dr Jose Aramburu (Immunology Lab, Universitat Pompeu Fabra)

Tuesday 26 June 2018

15:00 - ER-mitochondria contact and stress signalling
Professor Junjie Hu (Institute of Biophysics, Chinese Academy of Sciences)

Monday 2 July 2018

14:00 - A window of opportunity for allostery in the T cell Receptor
Prof Balbino Alarcon (National Research Council of Spain (CSIC), Center for Molecular Biology 'Severo Ochoa', Madrid, Spain)

Wednesday 11 July 2018

13:00 - Organ protection by antimicrobial/host-defence peptides
TBA

Friday 14 September 2018

13:00 - Exploring the signaling landscape of immune cell surface receptors
Ricardo A. Fernandes (Stanford University School of Medicine)

Wednesday 19 September 2018

13:00 - In vitro and in silico approaches to obtain tailored reagents - Nanobodies as a model
Dr Ario de Marco (Laboratory for Environmental and Life Sciences, University of Nova Gorica)

Friday 21 September 2018

13:00 - Promoter-proximal convergent antisense transcripts (PCATs): a novel class of regulatory non-coding RNAs
Dr Maria Carmo-Fonseca (IMM, Lisbon)

Tuesday 25 September 2018

Thursday 4 October 2018

15:00 - IIntegrin-mediated mechanotransduction: a driver of epithelia morphogenesis and homeostasis
Dr Lola Martin-Bermudo (CABD/Univ. Pablo de Olavide, Seville)

Wednesday 10 October 2018

13:00 - Organelle tethering during adipocyte differentiation
Dr Robin Klemm (University of Zurich)

Wednesday 17 October 2018

13:00 - Thymic commitment to gd T cell effector fate: Do IL-17-secreting gd T cells have a separate origin?
Prof Dan Pennington (Blizard Institute, Barts & The London School of Medicine and Dentistry)

Monday 22 October 2018

14:00 - How Does The Thymus Control Diversity in T-cell Development ?
Prof Graham Anderson (Institute of Immunology and Immunotherapy, University of Birmingham)

Wednesday 24 October 2018

13:00 - Crosstalk between epithelial cells and T cells at the intestinal barrier
Dr Mahima Swamy (School of Life Sciences, University of Dundee)

Thursday 25 October 2018

11:00 - Ubiquitin-mediated regulation of host factors during virus infections
Dr Sumana Sanyal (HKU - Pasteur Research Pole )

Monday 29 October 2018

15:30 - Role and mechanism of XBP1u-translational pausing in the unfolded protein response
Prof Kenji Kohno (NAIST, Ikomo, Japan)

Wednesday 7 November 2018

13:00 - Membrane-mediated cooperativity and domain formation of receptors and ligands in cell adhesion
Dr Thomas Weikl (Max Planck Institute of Colloids and Interfaces, Germany)

Monday 12 November 2018

14:00 - When fear kills: the case of nuclear energy
Prof Wade Allison (University of Oxford)

Wednesday 14 November 2018

13:00 - Deciphering key checkpoints in CD4 T cell responses’
Dr David Withers (University of Birmingham)

Tuesday 20 November 2018

14:00 - Chromatin-based Epigenetic Inheritance. Lessons from the Centromere
Dr Lars Jansen (Dept of Biochemistry, University of Oxford)

Wednesday 28 November 2018

11:00 - Molecular mechanisms of eukaryotic DNA replication and recombination
Dr Luca Pellegrini (University of Cambridge)

Thursday 29 November 2018

15:00 - On the origin of proteins from ancestral peptides
Dr Vikram Alva (Protein Bioinformatics, Max Planck Institute for Development Biology)

Thursday 6 December 2018

11:00 - Function and heptad-specific modification of Pol II CTD in the transcription cycle
Prof Dirk Eick (Research Unit Molecular Epigenetics, Helmholtz Center Munich)

Friday 7 December 2018

11:00 - Resolving mechanisms of protein organization and signalling at the cell membrane in single molecule detail
NOTE TIME CHANGE TO 11am.
Dr Eilon Sherman (Racah Institute of Physics, The Hebrew University of Jerusalem)

Monday 10 December 2018

15:00 - The Role of Seipin in Adipocyte Development and Lipid Droplet Biogenesis
Prof Hongyuan Robert Yang (School of Biotechnology and Biomolecular Sciences, Universityof New South Wales)

Tuesday 15 January 2019

11:00 - Defining how DNA replication stress impacts on faithful chromosome segregation'
Prof Ian Hickson (University of Copenhagen)

Thursday 24 January 2019

15:00 - Orchestrating T cell activation at the immunological synapse. Interplay between cytoskeleton and vesicle traffic
Dr Andres Alcover (Institut Pasteur, Paris, France)

Wednesday 6 February 2019

13:00 - Spatiotemporal organisation of immune signaling at the plasma membrane
Dr Erdinc Sezgin (University of Oxford)

Wednesday 13 February 2019

Monday 18 February 2019

11:00 - Sensing and Restricting: Innate Immune Control of Virus Infection
Dr Jan Rehwinkel (MRC Human Immunology Unit, WIMM, University of Oxford )

Friday 1 March 2019

11:00 - Elucidating the birth of blood and immune cells in mouse development
Professor Marella de Bruijn (University of Oxford, Weatherall Institute of Molecular Medicine)

Wednesday 20 March 2019

13:00 - Antigen regulation of distal TCR signalling dynamics
Dr David Bending (College of Medical and Dental Sciences, University of Birmingham)

Monday 1 April 2019

14:00 - A role for rhomboid protease RHBDL4 in Alzheimer’s disease
Dr Lisa Marie Münter (McGill University, Canada)

Friday 5 April 2019

13:00 - Battle to the end: how microbial pathogens evade innate immunity
Prof Ana Traven (Monash University, Melbourne, Australia)

Monday 15 April 2019

14:00 - New insights on Intraflagellar transport and flagellum length control in Trypanosoma brucei
Dr Eloise Bertiaux (Cell Biology Department (BICEL), University of Geneva)

Wednesday 8 May 2019

13:00 - Stochastic Gene Expression and Cell Size regulation
Dr Vahid Shahrazaei (Faculty of Natural Sciences, Department of Mathematics, Imperial College)

Wednesday 15 May 2019

13:00 - Selection events during antibody affinity maturation in germinal centres
Dr Oliver Bannard (University of Oxford)

Friday 31 May 2019

11:00 - Why is G2 phase not shorter?
Dr Arne Lindqvist (Karolinska Institutet, Stockholm)

Wednesday 12 June 2019

13:00 - Sleep, Amyloid beta, and Brain Lymphatic Endothelial Cells
Dr Jason Rihel (UCL)

Tuesday 2 July 2019

14:15 - Interplay of Transcription, Mutation & Replication in antibody maturation and genome instability in B cells
Dr Rushad Pavri (Research Institute of Molecular Pathology (IMP), Vienna)

Thursday 4 July 2019

11:00 - Centromere satellite DNA as a source of genome instability
Dr Simona Giunta (Rockefeller University)

Wednesday 17 July 2019

14:00 - Exploring Quantitative Aspects of Scanning Tramission EM for Cryo-Imaging and Tomography
Prof Michael Elbaum (Weizmann Institute of Science, Israel)

Friday 13 September 2019

14:00 - Recent Progress on the Molecular Mechanism and Clinical Importance of APOBEC Mutagenesis in Cancer
Prof Reuben Harris (University of Minnesota)

Monday 16 September 2019

14:00 - AvidCARs - a novel platform for integration of multiple input signals by one CAR molecule
Benjamin Salzer, MSc ( St. Anna Kinderkrebsforschung, Vienna, Austria )

Thursday 10 October 2019

15:00 - Impact of cell delamination on tissue morphogenesis
Dr Magali Suzanne (The Center for Integrative Biology in Toulouse (CBI Toulouse))

Thursday 7 November 2019

16:00 - Centriole overduplication, spindle misorientation and the consequences of abnormal mitosis
Dr Andrew Porter (CRUK Manchester Institute, University of Manchester)

Tuesday 12 November 2019

12:00 - NAD+ and Mitophagy in Brain Ageing and Neurodegenerative Disorders
Dr Evandro Fei Fang (University of Oslo)

Monday 25 November 2019

15:30 - Type I IFN-driven hyperinflammation and immune suppression in tuberculosis – two sides of the same coin?
Prof Igor Kramnik (University of Boston)

Monday 2 December 2019

14:00 - INTRACELLULAR IMMUNITY AS THE ORGANIZER OF HOST DEFENSE
Associate Professor Hans-Christian Reinecker (Harvard Medical School )

Friday 6 December 2019

13:00 - Dynamics in protein translation sustaining T cell preparedness
Prof Roger Geiger (IRB, Switzerland)

Wednesday 11 December 2019

13:00 - To die or not to die: how cells do their tricks
Dr Yun Fan (University of Birmingham)

Friday 13 December 2019

12:00 - Making a spindle in oocytes
Prof Hiro Ohkura (University of Edinburgh)

Monday 20 January 2020

14:00 - Finally: empty class I molecules
Dr Sebastian Springer (Jacobs University Bremen, Germany)

Tuesday 21 January 2020

15:00 - Molecular definition of lipid droplet diversity
Dr Ho Yi Mak (The Hong Kong University of Science & Technology)

Wednesday 22 January 2020

13:00 - How many TCR clonotypes does a body maintain?
Dr Grant Lythe (School of Mathematics, Leeds University)

Wednesday 12 February 2020

13:00 - Single-molecule imaging of GPCR contributions to T cell activation
Dr James Felce (The Kennedy Institute, Oxford)

Wednesday 19 February 2020

13:00 - I’ll kill you or I’ll protect you depending on how much you bother me (a story about the caspase-3/p120RasGAP stress-sensing module)
Dr Christian Widmann (University of Lausanne)

Wednesday 4 March 2020

13:00 - Pushing and pulling: Centrosome positioning in polarized cells
Dr Adriana Dawes (Dept of Mathematics, The Ohio State University)

Friday 13 March 2020

11:00 - Insights in pro-influenza virus activity of ANP32 proteins
CANCELLED
Status: This talk has been cancelled
Mr Ecco Staller (Imperial College, London)

Tuesday 24 March 2020

15:00 - Cryo-EM structures of polymeric autophagy and ESCRT assemblies
CANCELLED
Status: This talk has been cancelled
Prof. Carsten Sachse (EMBL in Heidelberg (Germany))

Wednesday 6 May 2020

13:00 - Complexity and communication in messenger RNA decay
Status: This talk has been cancelled
Dr Eugene Valkov (National Cancer Institute, NIH, Bathesda)

Wednesday 27 May 2020

13:00 - Modu-LAT-ing T cell receptor ligand discrimination
Status: This talk has been cancelled
Dr Wan-Lin Lo (University of California)

Wednesday 22 July 2020

11:00 - Cells within cells: rickettsiae and the obligate intracellular lifestyle
Status: This talk has been cancelled
Prof Jeanne Salje (NDM, Oxford)

Wednesday 19 August 2020

16:00 - Modu-LAT-ing T cell receptor ligand discrimination
Webinar Registration is required
Dr Wan-Lin Lo (University of California)

Wednesday 28 October 2020

13:00 - Mechanical regulation of antigen affinity discrimination in the follicular dendritic cell – B cell immune synapse
Via zoom https://zoom.us/j/97343782799?pwd=TnEwZ05HbHg1OFZIekRJa2lMRmNOdz09
Dr Katelyn Spillane (Department of Physics, King’s College London)

Friday 15 January 2021

09:25 - Research Techniques Day
This meeting is aimed at D. Phil students but scientists of all levels attend. Everyone is welcome
Various Speakers

Tuesday 2 February 2021

14:00 - Informing shigellosis control and management in resource poor settings through pathogen genomics
ZOOM LINK: https://us02web.zoom.us/j/82421870005
Dr Kate Baker (University of Liverpool)

Thursday 29 July 2021

09:30 - Molecular interaction analysis by grating coupled interferometry
TBA

Friday 27 August 2021

14:00 - Peptides & Protons: Transport and trafficking in human health and disease
Professor Simon Newstead (University of Oxford,)

Monday 13 September 2021

14:00 - ADP-ribosylation signalling in health and disease
Dr Ivan Ahel (Sir William Dunn School of Pathology, University of Oxford)

Friday 24 September 2021

14:00 - Evolution of function in metabolic networks
Dr Luiz Pedro Sório de Carvalho (The Francis Crick Institute - Mycobacterial Metabolism and Antibiotic Research Laboratory)

Monday 27 September 2021

14:00 - Investigating Human Foetal Blood Development at the Single-Cell Level
Dr Ana Cvejic (Dept of Haematology, WT-MRC Cambridge Stem Cell Institute)

Wednesday 29 September 2021

14:00 - How cells defend their cytosol from bacterial invasion: Ubiquitylation of LPS and other tricks
Professor Felix Randow (MRC Laboratory of Molecular Biology, Cambridge University)

Friday 15 October 2021

14:00 - Molecular structures and mechanisms of key components in DNA double-strand break signalling
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Professor Xiaodong Zhang (Imperial College, London)

Monday 18 October 2021

14:00 - Metabolic adaptation in disease tolerance to infection
Webinar only please contact Jo Peel for connection details, email: jo.peel@path.ox.ac.uk
Dr Miguel Soares (Instituto Gulbenkian de Ciência, Portugal)

Friday 29 October 2021

14:00 - CRAC et al. – Regulation of immune cell function by ion channels
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Stefan Feske (Jeffrey Bergstein Professor of Medicine, Department of Pathology, NYU Langone Health)

Monday 1 November 2021

14:00 - Unravelling the Challenges of Vaccine Development for Malaria: from Antibody Immunology to Rational Design
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Professor Simon Draper (University of Oxford)

Thursday 4 November 2021

15:00 - A view to a kill: insight into mechanisms of cytotoxic T cell killing and cancer cell resistance from dynamic imaging
https://us06web.zoom.us/j/85766095336?pwd=YkxWMExHdGNhT0RZM3hSdUVLbS9IZz09
Dr Alex Ritter (Genentech · Department of Cancer Immunology)

Monday 8 November 2021

14:00 - Pinning down protein conformational regulation: a new paradigm in signal transduction and drug discovery
This seminar is a webinar only. For connection details please contact: jo.peel@path.ox.ac.uk All members of the University of Oxford are welcome.
Kun Ping Lu (Professor, Program in Neuroscience, Harvard Medical School)

Friday 12 November 2021

14:00 - Mechanosensing and energy flux driving tumour cell metastasis
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Prof Laura Machesky (Professor of Cell Biology, Cancer Research UK, Beatson Institute, Glasgow / Director, Institute of Cancer Sciences, University of Glasgow)

Wednesday 17 November 2021

14:00 - Inflammatory circuits
This is is a Zoom webinar only and newly confirmed date to that previously advertised.
Professor Triantafyllos Chavakis (Institute for Clinical Chemistry and Laboratory Medicine, University Hospital and Faculty of Medicine, TU, Dresden, Germany)

Friday 19 November 2021

14:00 - Mechanotransduction in physiology and disease
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Dr Ellie Tzima (Cardiovascular Medicine, Radcliffe Department of Medicine)

Thursday 25 November 2021

14:00 - Intestinal antibodies: the importance of being specific?
Due to Covid security measures there are only 15 seats for an in-person audience in the EPA Seminar Room at the Dunn School. If you are unable to secure a seat please do join the webinar. Contact Jo Peel to book a seat and for webinar connection details. Email: jo.peel@path.ox.ac.uk
Professor Emma Slack (Department of Health Sciences & Technology, ETH Zürich)

Friday 10 December 2021

14:00 - Host-parasite interactions: from molecular mechanisms to precision therapeutics
Due to Covid security measures this seminar will now be online only. Please Contact Jo Peel for webinar connection details. Email: jo.peel@path.ox.ac.uk
Professor Matthew Higgins (Department of Biochemistry, University of Oxford)

Monday 7 February 2022

13:00 - Investigating surface proteins and swimming propellers in extremophilic archaea by cryoEM
Zoom Link: https://us06web.zoom.us/j/87641234933?pwd=Zy9WT2wzT2lLTUVjdGxjWkxySitZdz09
Dr Lavinia Gambelli (University of Exeter)

Friday 11 February 2022

14:00 - A difficult superbug: from armour to dormancy at molecular level
This is a hybrid seminar, with an in-person audience limited to 15 seats and virtual attendance via Zoom. Contact: jo.peel@path.ox.ac.uk to register.
Dr Paula Salgado (Biosciences Institute, Newcastle University)

Friday 18 February 2022

14:00 - R-loops in health and disease
This is a hybrid seminar, with an in-person audience limited to 15 seats and virtual attendance via Zoom. Contact: jo.peel@path.ox.ac.uk to register.
Dr Natalia Gromak (Dunn School of Pathology, University of Oxford)