• Type: Seminar Series
• Series organiser: Lorraine Dyson (University of Oxford)
• Web Address: https://www.opdc.ox.ac.uk/seminars-events
• Organising department: Department of Physiology, Anatomy and Genetics (DPAG)

Thursday 26 February 2015

• 16:00 - Unbiased Approaches to Parkinson's Disease Biomarker Discovery
  Prof. Alice Chen-Plotkin (Perelman School of Medicine, University of Pennsylvania)

Thursday 16 April 2015

• 16:00 - Neuroinflammation Influenced by Parkinson's Disease genes SNCA and LRRK2
  Status: This talk is in preparation - details may change
  TBA

Monday 20 April 2015

• 09:00 - OPDC Research Day 2015
  Abstract Submission closes Friday March 20th 2015 Registration closes on April 10th 2015 If you have any further queries please contact opdc.administrator@dpag.ox.ac.uk.
  TBA

Tuesday 5 May 2015

• 16:00 - Prof. Steven Gill "GDNF: Back to the Clinic"
  Professor Steven S Gill MB FRCS MS (Institute of Clinical Neurosciences, North Bristol NHS Trust)

Tuesday 24 November 2015

• 16:00 - Prof Giovanna Mallucci: Neurodegeneration: molecules to medicines
  Professor Giovanna Mallucci (Department of Clinical Neurosciences, University of Cambridge)

Tuesday 19 January 2016

• 16:00 - Elucidation of a set of validated physiological substrates for the Parkinson’s LRRK2 kinase
  Prof. Dario Alessi (MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee)

Tuesday 16 February 2016

• 16:00 - Does alpha-synuclein pathology spread in the brain?
  Professor Miquel Vila (Vall d’Hebron Research Institute (Barcelona))

Tuesday 15 March 2016

• 15:00 - Translational stem cell biology: Developing Cell Therapy for Parkinson's Disease
  Status: This talk is in preparation - details may change
  Professor Malin Parmar (Lund University )

Wednesday 6 April 2016

• 16:00 - The Function of alpha-Synuclein
  Status: This talk is in preparation - details may change
  Professor Robert Edwards (University of California, San Francisco)

Tuesday 10 May 2016

• 16:00 - Dr Valerio Zerbi - 'The structural basis of large-scale functional connectivity in the mouse'
  Status: This talk is in preparation - details may change
  Dr Valerio Zerbi (ETH Zurich)

Tuesday 21 June 2016

• 16:00 - Professor Jia-Yi Li - 'Prion-like pathology propagation in Parkinson’s disease: the present standing'
  Status: This talk is in preparation - details may change
  Professor Jia-Yi Li (Lund University)

Tuesday 12 July 2016

• 16:00 - Cellular processing of Alpha-synuclein : implications for Parkinson’s Disease
  Mark Cooper (UCL Institute of Neurology)

Tuesday 27 September 2016

• 16:00 - Emulating physiological dopamine receptor activation in Parkinson’s Disease
  Professor John Reynolds (University of Otago Medical School)

Tuesday 25 October 2016

• 16:00 - Title TBC
  Status: This talk has been cancelled
  Dr Alastair Noyce (University College London)

Tuesday 15 November 2016

• 16:00 - What if we could target ageing in Parkinson’s disease?
  Mickael Decressac (Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy)

Thursday 8 December 2016

• 16:00 - Huntington’s Disease In A Dish: Current progress and future perspectives
  Professor Nick Allen (University of Cardiff)

Wednesday 14 December 2016

• 15:00 - Making the most of your microscopy images with CellProfiler and CellProfiler Analyst
  Dr Beth Cimini (Broad Institute of MIT and Harvard)

Tuesday 17 January 2017

• 16:00 - Transgenic models of Parkinson's disease
  Olaf Horst Rieß (University of Tübingen)

Tuesday 14 February 2017

• 12:00 - Deadly cargoes: extracellular synuclein and Parkinson's disease progression
  Please note TALK AT NOON. Entrance to the Sherrington building will be via the temporary reception at the entrance to The Burdon Sanderson Cardiac Science Centre
  Kostas Vekrellis (Biomedical Research Foundation of the Academy of Athens)

Monday 20 March 2017

• 09:15 - OPDC Research Day
  Abstract Submission closes Friday February 17th 2017
  Prof. Dr. Birgit Liss (Ulm University), Professor Masud Husain (University of Oxford), Professor Richard Wade-Martins (Professor of Molecular Neuroscience, University of Oxford), Dr Thomas Barber (University of Oxford ), Siddharth Arora (University of Oxford ), Johannes Klein (University of Oxford), Dr George Tofaris (University of Oxford ), Dr Laura Parkkinen (University of Oxford ), Dr Jimena Monzon Sandoval (University of Oxford ), Dr Dayne Beccano-Kelly (University of Oxford), Dr Brent Ryan (University of Oxford ), Dr Natalie Connor-Robson (Oxford Parkinson's Disease Centre (OPDC), DPAG, University of Oxford), Dr Paul Dodson (University of Oxford, MRC Anatomical Neuropharmacology Unit), Dr Sarah Threlfell (University of Oxford )

Tuesday 25 April 2017

• 16:00 - Gene-environment interactions: a success story in Parkinson’s disease
  Prof Beate Ritz (School of Public Health at UCLA)

Monday 15 May 2017

• 16:00 - Molecular and structural determinants of Alpha-Synuclein aggregation, toxicity and pathology spreading in Parkinson's disease: From mechanisms to novel biomarkers and therapies
  PLEASE NOTE New Date
  Hilal Lashuel (Swiss Federal Institute of Technology)

Tuesday 23 May 2017

• 16:00 - Cerebrospinal and serum alpha-synuclein species as potential biomarkers for Parkinson’s disease
  Please note, talk in small lecture theatre
  Prof. Omar El-Agnaf (Qatar Biomedical Research Institute)

Tuesday 13 June 2017

• 16:00 - Applications of high throughput single cell analysis and deep learning to iPSC models of Parkinson’s disease and neurotherapeutics
  Prof Steven Finkbeiner (UCSF)

Wednesday 19 July 2017

• 16:00 - Targeting mitochondrial biogenesis and function in Parkinson’s disease
  Please note now WEDNESDAY July 19th
  Michela Deleidi (DZNE)

Tuesday 8 August 2017

• 16:00 - Inflammation & Neurodegeneration: a Role for Toll-like Receptors
  Kathleen Maguire-Zeiss (University of Georgetown)

Tuesday 12 September 2017

• 16:00 - Of genes and mechanisms: cell biology of PD
  Dr Mattia Volta (​​​​​​European Academ​​y of Bolzano/Bozen (EURAC) )

Friday 6 October 2017

• 13:00 - Parkinson’s progress: novel genes, mouse models and synthesis
  Professor Matt Farrer (University of British Columbia)

Wednesday 15 November 2017

• 16:00 - Biomarkers in Parkinson’s disease
  Dr Brit Mollenhauer (University Medical Center of Goettingen (UMG-GOE))

Tuesday 12 December 2017

• 16:00 - Parkinson’s Disease Seen from the alpha-Synuclein Perspective
  Professor Donato A. Di Monte (German Center for Neurodegenerative Diseases (DZNE))

Tuesday 16 January 2018

• 16:00 - Parkinson's disease: environmental clues and transporter blues
  Professor Gary Miller (Rollins School of Public Health, Emory University)

Friday 19 January 2018

• 11:30 - REM Sleep Behaviour Disorder: from circuits to pathology
  Pierre-Hervé Luppi (Centre de recherche en neurosciences de Lyon)

Tuesday 23 January 2018

• 12:00 - Cell type-specific translation profiling in fragile X
  Dr Emily Osterweil (University of Edinburgh)

Tuesday 13 February 2018

• 12:00 - Immune and inflammatory mechanisms underlying risk for age-related neurodegenerative disease
  Please note new time!
  Prof. Malú Tansey (Emory University School of Medicine)

Tuesday 13 March 2018

• 16:00 - Gene therapies for Parkinson's disease
  Stephane Palfi (IMRB - Mondor Biomedical Research Institute)

Tuesday 10 April 2018

• 16:00 - Achieving Neuroprotection in Parkinson’s Disease
  Andy West (UAB School of Medicine)

Wednesday 16 May 2018

• 16:00 - Local and global facets of sleep regulation
  Prof. Vlad Vyazovskiy (Department of Physiology, Anatomy and Geneitcs, University of Oxford)

Wednesday 13 June 2018

• 12:00 - Mitophagy modulation as a potential therapeutic target for neurodegenerative diseases
  Please note this talk is now at NOON in the Small Lecture Theatre
  Dr Hélène Plun-Favreau (UCL Institute of Neurology)

Tuesday 18 September 2018

• 16:00 - Behaviour and synaptic plasticity in a model of early Parkinson's: the role of alpha-synuclein
  Dr Barbara Picconi (IRCCS San Raffaele University, Rome, Italy.)

Tuesday 2 October 2018

• 09:00 - OPDC Parkinson's Research Day
  Registration for the 2018 OPDC research day is free and includes refreshments, lunch and reception. Please complete the registration form below to join us at this exciting event. Registration closes on September 26th 2018
  Various Speakers

Monday 19 November 2018

• 12:00 - Using transcriptomics to understand neurodegenerative disorders
  PLEASE NOTE NEW TIME!
  Dr Mina Ryten (UCL)

Wednesday 12 December 2018

• 16:00 - Challenges and Opportunities of Translational Neurogenomics
  Dr Sonja Scholz (Neurodegenerative Diseases Research Unit, NIND, NIH)

Wednesday 13 February 2019

• 12:00 - Molecular pathways to Parkinson's disease: more than neurons?
  Note earlier time
  Dr. Elisa Greggio (University of Padova)

Wednesday 27 March 2019

• 16:00 - LRRK2 Mediated Cellular Function from Vesicular Trafficking to Gene Expression
  Professor Kirsten Harvey (UCL School of Pharmacy)

Tuesday 16 April 2019

• 16:00 - Pathway to Parkinson’s Disease: A Tale of Two Genes
  Darren Moore (Van Andel Research Institute)

Tuesday 14 May 2019

• 16:00 - Unconventional Endoplasmic Reticulum Located Trophic Factor for Parkinson’s Disease
  New date!
  Professor Mart Saarma (Institute of Biotechnology, University of Helsinki)

Wednesday 12 June 2019

• 12:00 - The toxic consequences of protein aggregation in Parkinson's disease
  Please note this talk is at noon.
  Dr Sonia Gandhi ( UCL Queen Square Institute of Neurology)

Thursday 11 July 2019

• 12:00 - The Quest for Neuroprotection in Parkinson’s disease: reversing synaptic dysfunction
  Please note this talk is at noon in the small lecture theatre
  Austen Milnerwood (McGill University)

Tuesday 16 July 2019

• 16:00 - Shining light on Parkinson’s disease by interrogating the LRRK2 kinase pathway
  Esther Sammler (University of Dundee)

Tuesday 17 September 2019

• 12:00 - Mechanisms of axon degeneration in injury and disease.
  Please note talk is at noon
  Professor Michael Coleman (University of Cambridge)

Tuesday 15 October 2019

• 16:00 - Striatal synaptic dysfunction in Parkinson's disease
  Professor Paolo Calabresi (University of Perugia, Italy)

Monday 28 October 2019

• 12:00 - The magic in the web of it: How a rare disorder is helping to untangle the mysteries of Parkinson’s disease
  Dr Ellen Sidransky (NIH)

Tuesday 12 November 2019

• 12:00 - NAD+ and Mitophagy in Brain Ageing and Neurodegenerative Disorders
  Dr Evandro Fei Fang (University of Oslo)

Wednesday 13 November 2019

• 10:00 - Synaptic alterations in the indirect-pathway of the basal ganglia in experimental Parkinsonism
  Jerome Baufreton (The Neuroscience Institute at Bordeaux)

Monday 20 January 2020

• 16:00 - Proteostasis and Mitochondrial Pathways in the Pathogenesis and Treatment of Parkinson’s Disease
  Dr Matthew LaVoie (Brigham and Women’s Hospital and Harvard Medical School)

Monday 3 February 2020

• 16:00 - Combining iPSCs and ‘omics to identify molecular convergence in neurodegenerative disorders
  Dr Michael Ward (National Institute of Neurological Disorders & Stroke (NINDS))

Monday 9 March 2020

• 16:00 - Mitophagy: from genetics to biology, and back
  Dr Hélène Plun-Favreau (UCL Institute of Neurology)

Monday 18 May 2020

• 14:00 - An update on the quest for genetic determinants in Parkinson's Disease and related disorders
  Professor Vincenzo Bonifati (Erasmus University Medical Center, Rotterdam)

Monday 15 June 2020

• 14:00 - Selective brain region vulnerability in Parkinson’s Disease is governed by α-Synuclein conformations
  This seminar will be held online. Email: opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Tim Bartels (Dementia Research Institute at the University College London)

Monday 6 July 2020

• 14:00 - Exploring human brain structure and function using cerebral organoids
  This seminar will be held online. Email: opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Madeline Lancaster (Medical Research Council Laboratory of Molecular Biology, part of the Cambridge Biomedical Campus)

Tuesday 22 September 2020

• 14:00 - Function and Dysfunction of Synucleins – Membranes Matter
  This seminar will be held online. Please email opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Jacqueline Burré (Brain and Mind Research Institute at Weill Cornell Medicine, New York)

Tuesday 13 October 2020

• 15:00 - Time to revise the classical model of basal ganglia dysfunction in Parkinson's Disease: New insights from a novel, progressive mouse of mitochondrial complex I dysfunction
  This seminar will be held online. Please email opdc.administrator@dpag.ox.ac.uk for more details.
  Dr D. James Surmeier (Northwestern University, Chicago)

Monday 9 November 2020

• 14:00 - Decoding Parkinson’s Disease: New Therapeutic Opportunities
  This seminar will be held online. Please email opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Valina Dawson (John Hopkins University School of Medicine)

Thursday 10 December 2020

• 14:00 - Mechanisms of Innate Immunity and Parkinson’s Disease
  Dr Richard Youle (National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health (NIH))

Tuesday 26 January 2021

• 14:00 - Tales from the human brain: a multi-scale approach to elucidate pathogenic mechanisms involved in Parkinson’s
  This seminar will be held online. Please email opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Wilma van de Berg (Amsterdam UMC)

Tuesday 9 February 2021

• 13:00 - CRISPR-Cas9 genetic screens to ameliorate cellular stress in neurodegeneration
  Dr. Emmanouil Metzakopian (UK Dementia Research Institute (UK DRI), University of Cambridge)

Tuesday 9 March 2021

• 14:00 - Modulation of striatal circuits by midbrain dopamine neurons
  Dr. Nicolas Tritsch (Neuroscience Institute and Marlene & Paulo Fresco Institute for Parkinson’s & Movement Disorders, New York University)

Monday 19 April 2021

• 13:00 - Mitochondrial DNA at the interface between mitochondrial dysfunction and inflammation in Parkinson’s disease
  Dr. Anne Grünewald (University of Luxembourg)

Monday 17 May 2021

• 13:00 - Body-first & Brain-first Parkinson's disease - explaining motor asymmetry, non-motor subtypes, and dementia
  This seminar will be held online. Please email opdc.administrator@dpag.ox.ac.uk for more details.
  Dr Per Borghammer (Aarhus University, Denmark)

Tuesday 22 June 2021

• 13:00 - Mitophagy dysfunction in autosomal recessive Parkinson’s disease: is it the whole story?
  Dr Olga Corti (Institut du Cerveau – Paris Brain Institute)

Tuesday 6 July 2021

• 14:00 - Sub-second Striatum Neuromodulatory Signaling on Multiple Spatial Scales During Learning and Action
  Dr Mark Howe (Boston University)

Wednesday 22 September 2021

• 13:00 - Autophagy and neurodegeneration
  Professor David Rubinsztein (University of Cambridge.)

Tuesday 12 October 2021

• 14:00 - Synaptic Vesicle Endocytosis and Parkinson’s disease
  Dr Sreeganga Chandra (Yale School of Medicine)

Monday 22 November 2021

• 14:00 - Modulators of pathology progression in neurodegenerative disease
  PLEASE NOTE CHANGE OF DATE TO MONDAY 22ND NOVEMBER
  Dr Michael Henderson (Van Andel Institute)

Tuesday 7 December 2021

• 13:00 - Molecular and functional organization of the mouse striatum
  Prof. Konstantinos Meletis (Dept. of Neuroscience, Karolinska Institutet, Stockholm, Sweden)

Thursday 20 January 2022

• 14:00 - Intracellular Membrane Lipid Dynamics and Neurodegenerative Diseases
  Professor Pietro De Camilli (Yale University School of Medicine, Kavli Institute for Neuroscience New Haven, CT USA)

Friday 11 February 2022

• 14:00 - Making sense of the exuberant axonal connectivity of dopamine neurones
  Professor Louis-Eric Trudeau (Faculty of Medicine Université de Montréal)

Wednesday 18 May 2022

• 14:00 - A hidden regulator of neuromodulation and motor learning: Protein synthesis by the integrated stress response (ISR)
  Dr Nicole Calakos (Dept. of Neurology, Duke University, School of Medicine)

Tuesday 24 May 2022

• 12:15 - The drug development landscape in Parkinson's
  This event will be held in person. Please note slightly the later start time of 12:15pm
  Dr Kevin McFarthing (Research Advisor, Parkinson’s UK Oxford Branch)

Monday 27 June 2022

• 14:00 - The role of LRRK2 in familial and sporadic Parkinson’s disease
  Dr. Mark R. Cookson (Laboratory of Neurogenetics, National Institute on Aging (NIA))

Wednesday 6 July 2022

• 14:00 - Cell circuits, progression genetics, and the quest to solve Parkinson’s with precision medicine
  Dr Clemens Scherzer (Harvard Medical School)

Monday 31 October 2022

• 16:00 - LRRK2 kinase in Parkinson’s disease: from single molecule to the brain
  The date of this seminar has changed
  Suzanne Pfeffer, Ph.D. (Stanford University School of Medicine)

Wednesday 25 January 2023

• 14:00 - Prodromal PD-definition and impact for clinical studies
  Dr. Daniela Berg, (University Medical Center Schleswig-Holstein, Germany)

Monday 27 February 2023

• 14:00 - Inflammation and immune dysfunction in Parkinson’s disease: targeting the gut-brain axis to reduce risk and progression
  Professor Malú Gámez Tansey (University of Florida)

Thursday 30 March 2023

• 14:00 - Mechanisms and Roles of Fast Dopamine Signaling
  Professor Pascal Kaeser (Harvard Medical School)

Monday 24 April 2023

• 14:00 - Genetics of synucleinopathies and how it informs us towards future clinical trials
  Dr Ziv Gan-Or (McGill University)

Monday 15 May 2023

• 14:00 - The cellular phase of Parkinson’s disease
  Professor Patrik Verstreken (Leuven Brain Institute)

Wednesday 28 June 2023

• 14:00 - Beyond Alpha-Synuclein: Exploring the Diversity of Molecular Mechanisms Underlying Parkinson's Disease
  Dr Ted. M. Dawson (Johns Hopkins University School of Medicine)

Wednesday 5 July 2023

• 13:00 - Towards Intraneuronal Immunotherapy (in person talk)
  Dr Ole Tietz (Dementia Research Centre, Macquarie Medical School, Macquarie University, NSW, Australia)

Monday 17 July 2023

• 13:00 - New stratification concepts for precision medicine in the diagnosis and treatment of Parkinson’s disease (in person talk)
  Prof. Rejko Krüger (Luxembourg Institute of Health)

Tuesday 24 October 2023

• 16:00 - Striatal Circuitry in Parkinson's Disease and Levodopa-Induced Dyskinesia
  Dr Alexandra Nelson (University of California)

Thursday 16 November 2023

• 12:00 - Exploring the crosstalk between familial and idiopathic Parkinson’s (in person talk)
  Dr Patrick Lewis (Royal Veterinary College, London)

Tuesday 21 November 2023

• 13:00 - Somatic mutations in the brain: do they have a role in synucleinopathies? (in person talk)
  Professor Christos Proukakis (University College London)

Wednesday 6 December 2023

• 16:00 - Rethinking Parkinson’s disease pathophysiology & how to model it with a focus on alpha-synuclein & cell autonomous processes
  Professor Poul Henning Jensen (Aarhus University, Denmark)

Tuesday 9 January 2024

• 14:00 - OPDC Seminar - Gene therapy to study and treat Parkinson’s disease
  Dr Michael G. Kaplitt (Weill Cornell Medicine, Brain, and Spine Center)

Tuesday 6 February 2024

• 12:00 - THIS EVENT HAS BEEN POSTPONED AND WILL BE REARRANGED FOR LATER IN THE YEAR Mitochondria at neuronal synapses: why are they there?
  THIS EVENT HAS BEEN POSTPONED AND WILL BE REARRANGED FOR LATER IN THE YEAR
  Dr Mike Devine (Francis Crick institute)

Monday 25 March 2024

• 12:00 - Dissecting Parkinson's disease with long-read RNA-sequencing
  Professor Mina Ryten (Cambridge Dementia Research Institute)

Wednesday 5 June 2024

• 12:00 - Mitophagy, from genetics to biology, and back (rescheduled date)
  Professor Hélène Plun-Favreau (University College London)

Thursday 20 June 2024

• 12:00 - Gut Macrophages Modulate Body-First Synucleinopathies
  Dr Tim Bartels (Dementia Research Institute at the University College London)

Thursday 18 July 2024

• 12:00 - Imaging Oligomers of Alpha-Synuclein in Parkinson’s Disease
  Professor Steven. F. Lee (University of Cambridge)

Tuesday 8 October 2024

• 16:00 - Intersection between innate immunity, lysosome damage and Parkinson’s disease
  Dr Shawn Ferguson (Yale School of Medicine)

Thursday 14 November 2024

• 16:00 - The interplay of peripheral of immune cells associated cytokines with induced pluripotent stem cell astrocytes; implications for Parkinson’s Disease
  Professor Maeve Caldwell (Trinity College Dublin)

Tuesday 19 November 2024

• 12:00 - Mitochondria at neuronal synapses: why are they there?
  Dr Mike Devine (Francis Crick institute)

Thursday 28 November 2024

• 11:00 - Neuronal Cell Biology of PINK1/Parkin mitophagy
  A/Professor Michael Lazarou (Walter and Eliza Hall Institute of Medical Research (WEHI) Parkville, Australia)

Wednesday 15 January 2025

• 12:00 - From bench to bedside - drug discovery for Parkinson's disease
  Professor Oliver Bandmann (Sheffield Institute for Translational Neuroscience)